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A purine and pyrimidine requiring mutant of Drosophila melanogaster

Published online by Cambridge University Press:  14 April 2009

E. R. Vyse  and
J. H. Sang
E. R. Vyse
Affiliation:
School of Biology, Sussex University, Brighton, England
J. H. Sang
Affiliation:
School of Biology, Sussex University, Brighton, England
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Summary

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The E.M.S.-induced auxotrophic mutant 1308 of Drosophila is located between 13·7 and 21·0 on chromosome 1. Survival of larvae is possible if whole RNA is provided in the diet, and this is shown to be a requirement for a source of both purines and pyrimidines. A proportion of larvae will grow on pyrimidine nucleosides alone. Tests for utilization of bases and of precursors suggest that 1308 is a double mutant, and not a single mutation preventing the synthesis of a common precursor of purines and pyrimidines.

Type
Short Papers
Information
Genetics Research , Volume 18 , Issue 1 , August 1971 , pp. 117 - 121
Copyright
Copyright © Cambridge University Press 1971

References

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