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Profiles of electrophoretic alleles in natural populations

Published online by Cambridge University Press:  14 April 2009

A. H. D. Brown ,
D. R. Marshall  and
L. Albrecht
A. H. D. Brown
Affiliation:
Division of Plant Industry, CSIRO, Canberra, Australia
D. R. Marshall
Affiliation:
Division of Plant Industry, CSIRO, Canberra, Australia
L. Albrecht
Affiliation:
Division of Plant Industry, CSIRO, Canberra, Australia
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Summary

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The charge state model of Ohta & Kimura (1973) for the number of electrophoretically detectable alleles in a finite population, is extended to include mutations of both one and two charge changes. The effective number of alleles (ne) is increased only slightly by this extension. Electrophoretic profiles of neutral variants are shown on average to be leptokurtic and have their odd central moments equal to zero. The expected frequency distribution of pairs of gametes which differ by 1,2,3,… charge units can be obtained as the sum of the appropriate terms from two geometric series.

Type
Research Article
Information
Genetics Research , Volume 25 , Issue 2 , April 1975 , pp. 137 - 143
Copyright
Copyright © Cambridge University Press 1975

References

REFERENCES

Ayala, F. J. (1972). Darwinian versus non-Darwinian evolution in natural populations of Drosophila. Proceedings 6th Berkeley Symposium Mathematical Statistics and Probability, v, 211–236.Google Scholar
Bernstein, S. C., Throckmorton, L. H. & Hubby, J. L. (1973). Still more genetic variability in natural populations. Proceedings of National Academy Sciences U.S.A. 70, 3928–3931.CrossRefGoogle ScholarPubMed
Kimura, M. (1955). Random genetic drift in multiallelic locus. Evolution 9, 419–435.CrossRefGoogle Scholar
Kimura, M. & Ohta, T. (1971). Protein polymorphism as a phase of molecular evolution. Nature 229, 467–469.CrossRefGoogle ScholarPubMed
King, J. L. (1974). Isoallele frequencies in very large populations. Genetics 76, 607–613.CrossRefGoogle ScholarPubMed
Lewontin, R. C. & Hubby, J. L. (1966). A molecular approach to the study of genic heterozygosity in natural populations. II. Amount of variation and degree of heterozygosity in natural populations of Drosophila pseudoobscura. Genetics 54, 595–609.CrossRefGoogle Scholar
Li, C. C. (1955). Population Genetics. University of Chicago Press.Google Scholar
Marshall, D. R. & Brown, A. H. D. (1974). The charge-state model of protein polymorphism in natural populations. Journal of Molecular Evolution (in the Press).Google Scholar
Ohta, T. & Kimura, M. (1973). A model of mutation appropriate to estimate the number of electrophoretically detectable alleles in a finite population. Genetical Research 22, 201–204.CrossRefGoogle Scholar
Ohta, T. & Kimura, M. (1974). Simulation studies on electrophoretically detectable genetic variability in a finite population. Genetics 76, 615–624.CrossRefGoogle Scholar