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Polymorphism of lactate dehydrogenase B subunit in rat erythrocytes
Published online by Cambridge University Press: 14 April 2009
Summary
Lactate dehydrogenase regulator gene Ldr-1 controls the amount of the lactate dehydrogenase A subunit in rat serum and the amount of lactate dehydrogenase B subunit in rat erythrocytes because no recombinant rats were found among 295 pups produced in the BDIV × (ACI × BDIV)F1 and (ACI × DI) Fl × DI backcrosses. Two alleles regulate the high (Ldr-1a) and low (Ldr-1b) activity enzyme. The Ldr-1 is not linked to hooded coat pattern or glyoxalase-1. Sex and Ldr-1 assorted independently; hence the gene is autosomal.
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