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Polymorphism at the G6PD and 6PGD loci in Drosophila melanogaster

II. Evidence for interaction in fitness

Published online by Cambridge University Press:  14 April 2009

R. Bijlsma
R. Bijlsma
Affiliation:
Biology Centre, Department of Genetics, University of Groningen, Haren (Gn), The Netherlands
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The influence of sodium octanoate on the polymorphism at the loci G6PD and 6PGD in Drosophila melanogaster was investigated by studying its effect on egg hatchability, larval-to-adult survival and adult survival. The results demonstrate the existence of differences in fitness between the different genotypes of the two loci both for larval-to-adult survival and for adult survival. Furthermore, changes in enzyme activity of both enzymes, brought about by the sodium octanoate treatment, were observed. This makes it highly probable that the observed differences in fitness can be ascribed to the loci themselves and not to linked fitness genes. Finally, this study demonstrates the existence of strong interaction between the two loci with respect to fitness. Epistasis was demonstrated both in the larval-to-adult survival experiment and in the adult survival experiment.

Type
Research Article
Information
Genetics Research , Volume 31 , Issue 3 , June 1978 , pp. 227 - 237
Copyright
Copyright © Cambridge University Press 1978

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