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A note on the theory of artificial selection in finite populations and application to QTL detection by bulk segregant analysis

Published online by Cambridge University Press:  01 August 1998

WILLIAM G. HILL
WILLIAM G. HILL
Affiliation:
Institute of Cell, Animal and Population Biology, University of Edinburgh, West Mains Road, Edinburgh EH9 3JT, UK
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Abstract

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Formulae are given for computing the distribution of numbers of selected individuals of each genotype and thus change in gene frequency at a locus with a large effect on a quantitative trait under truncation selection in a finite population. Results are illustrated with respect to use of selection for quantitative trait locus (QTL) detection, specifically by bulk segregant analysis with linked markers, for which probabilities that selected samples will comprise almost all one genotypic class are computed.

Type
SHORT PAPER
Information
Genetics Research , Volume 72 , Issue 1 , August 1998 , pp. 55 - 58
Copyright
© 1998 Cambridge University Press