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A note on the inheritance of erythromycin-resistance in Paramecium aurelia

Published online by Cambridge University Press:  14 April 2009

G. H. Beale
Affiliation:
Institute of Animal Genetics, Edinburgh
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In yeast it has been reported that some types of erythromycin-resistance are due to cytoplasmic genetic factors, localized in mitochondria (Thomas & Wilkie, 1968; Slonimski, 1969). In view of the current interest in genetical aspects of mitochondria, and the ease with which cytoplasmic heredity can be demonstrated in Paramecium aurelia, some tests have been made to determine whether erythromycin-resistant variants could be obtained in this ciliate and, if so, to determine their genetic basis.

Type
Short Papers
Copyright
Copyright © Cambridge University Press 1969

References

REFERENCES

Beale, G. H. (1954). The Genetics of Paramecium aurelia. Cambridge.Google Scholar
Slonimski, P. (1969). Mitochondrial DNA in yeast in relation to mutational or recombinational events. In The Development and Interrelationships of Cell Organelles. Symp. Soc. exp. Biol. (in the Press).Google Scholar
Sonneborn, T. M. (1950). Methods in the general biology and genetics of Paramecium aurelia. J. exp. Zool. 113, 87143.CrossRefGoogle Scholar
Thomas, D. Y. & Wilkie, D. (1968). Inhibition of mitochondrial synthesis in yeast by erythromycin: cytoplasmic and nuclear factors controlling resistance. Genet. Ree., Camb. 11, 3341.CrossRefGoogle ScholarPubMed