Hostname: page-component-586b7cd67f-rcrh6 Total loading time: 0 Render date: 2024-11-26T14:45:32.602Z Has data issue: false hasContentIssue false
  • English
  • Français

Non-disjunction and maternal age in D. melanogaster

Published online by Cambridge University Press:  14 April 2009

P. Kelsall
P. Kelsall
Affiliation:
Institute of Animal Genetics, Edinburgh, 9
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The frequencies of non-disjunction at first and second meiotic division, in both male and female of Drosophila melanogaster, are estimated. Numbers of exceptional individuals scored in several broods of increasing parental age are also presented. These results fail to show any evidence of an age-effect. Work claiming to demonstrate the existence of an age effect in Drosophila is reinvestigated. The importance of these results and their relevance to human studies are discussed.

Type
Research Article
Information
Genetics Research , Volume 4 , Issue 2 , July 1963 , pp. 284 - 289
Copyright
Copyright © Cambridge University Press 1963

References

REFERENCES

Anderson, E. G. (1927). A comparison of the percentages of non-disjunction in successive broods. Pap. Mich. Acad. Sci. 7, 273–278.Google Scholar
Bridges, C. B. (1913). Non-disjunction of the sex-chromosomes of Drosophila. J. exp. Zool. 15, No. 4.Google Scholar
Kelsall, P. J. (1961). Non-disjunction of the sex-chromosomes in the male of D. melanogaster. Nature, Lond., 190, 1035–1036.CrossRefGoogle Scholar
Lamy, R. (1949). Production of 2-X sperm in males. D I.S. 23, 91.Google Scholar
Lenz, W., Nowackowski, H., Prader, A. & Schirren, C. (1959). Die Ätioligie des Kline-felter-syndroms. Schweiz. Wschr. 89, 727.Google Scholar
Mottram, J. C. (1930). The effect of carbon dioxide on the occurrence of non-disjunction in Drosophila. J. exp. Biol. VII, No. 4, 370–372.CrossRefGoogle Scholar
Penrose, L. S. (1933). The relative effects of paternal and maternal age in mongolism. J. Genet. 27, 219–224.CrossRefGoogle Scholar
Penrose, L. S. (1957). Parental age in achondroplasia and mongolism. Amer. J. hum. Genet. 9, 167–169.Google ScholarPubMed
Safir, S. R. (1920). Genetic and cytological examination of the phenomenon of primary N.D. in D. melanogaster. Genetics, 5, 459–487.CrossRefGoogle Scholar
Slizynski, B. M. (1960). Sexual dimorphism in mouse gametogenesis. Genet. Res. 1, 477–486.CrossRefGoogle Scholar
Smith, D. W., Patau, K., Therman, E. & Inhorn, S. L. (1962). The No. 18 trisomy syndrome. Amer. J. Pediatrics, St. Louis, 60, No. 4, 513–527.Google ScholarPubMed
Stewart, J. S. S. (1960). Mechanism of meiotic non-disjunction in man. Nature, Lond., 187, 804–805.CrossRefGoogle ScholarPubMed