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Neighbour mapping as a method for ordering genetic markers

Published online by Cambridge University Press:  01 February 1997

T. H. N. ELLIS
Affiliation:
Department of Applied Genetics, John Innes Centre, Colney Lane, Norwich NR4 7UH, UK
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Abstract

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A modification of the neighbour joining method of Saitou & Nei (1987) is shown to be applicable to the ordering of genetic markers. This neighbour mapping method is compared with some other procedures for ordering genetic markers using both real and test data sets. The limitations and likely errors associated with the use of neighbour mapping are discussed. The speed and simplicity of this method commend its application, as does its concurrence with other mapping methods.

Type
Research Article
Copyright
© 1997 Cambridge University Press