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Mapping an invisible lethal in the mouse
Published online by Cambridge University Press: 14 April 2009
Summary
An effective breeding policy is described for detecting linkage in the mouse, for an ante-natal lethal from crosses of heterozygotes with stocks homozygous for several linked recessive markers. A method of analysing the ensuing data is described, together with a method of estimating the map distance to close markers. A practical illustration is described, involving an ante-natal lethal obtained from a colony of wild mice and a four fold recessive chromosome 2 marker stock.
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- Copyright © Cambridge University Press 1976