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Linkage relations and some pleiotropic effects of the dreher mutant of the house mouse

Published online by Cambridge University Press:  14 April 2009

Mary F. Lyon
Affiliation:
Medical Research Council Radiobiological Research Unit, Harwell, Berkshire, England
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Linkage studies with the mutant dreher (dr) of the mouse (Mus musculus L.) have shown that it lies in linkage group XIII and that the order of loci is dr–Dh–ln. The recombination between dr and Dh was 22·3 ± 4·1%.

Two previously undescribed pleiotropic effects of the dr gene were observed. The first was a tendency to white spotting in the belt region, and the second an interaction with brachyury (T) such that drdr T+ animals had shorter tails on the average than + dr T +.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1961

References

REFERENCES

Bierwolf, D. (1958). Die Embryogenese des Hydrocephalus und der Kleinhirnmissbildungen beim Dreherstamm der Hausmaus. Morph. Jb. 99, 542612.Google Scholar
Carter, T. C. (1957). Private communication. Mouse News Letter, 16, 15.Google Scholar
Falconer, D. S. & Sierts-Roth, U. (1951). Dreher, ein neues Gen der Tanzmausgruppe bei der Hausmaus. Z. indukt. Abstamm.- u. VererbLehre, 84, 7173.Google Scholar
Fischer, H. (1956). Morphologische und mikroskopischanatomische Untersuchungen am Innenohr eines Stammes spontanmutierter Hausmäuse (Dreher). Z. mikr.-anat. Forsch. 62, 348406.Google Scholar
Fischer, H. (1958). Die Embryogenese der Innenohrmissbildungen bei dem spontanmutierten Dreherstamm der Hausmaus. Z. mikr.-anat. Forsch. 64, 476497.Google Scholar
Fisher, R. A. (1946). A system of scoring linkage data, with special reference to the pied factors in mice. Amer. Nat. 80, 568578.CrossRefGoogle Scholar
Searle, A. G. (1959). Hereditary absence of spleen in the mouse. Nature, Lond., 184, 1419.CrossRefGoogle Scholar