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Linkage disequilibrium, genetic distance and evolutionary distance under a general model of linked genes or a part of the genome*

Published online by Cambridge University Press:  14 April 2009

Naoyuki Takahata
Naoyuki Takahata
Affiliation:
National Institute of Genetics, Mishima, Shizuoka-ken 411, Japan
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Summary

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A general model of linked genes or a part of a genome is proposed which enables us to study various problems in molecular population genetics in a unified way. Several formulae with special reference to the linkage disequilibrium and genetic distance are derived for neutral mutations in finite populations, based on the method of diffusion equations. It is argued that the model and formulae are useful particularly when observations are made in terms of DNA sequence.

Type
Research Article
Information
Genetics Research , Volume 39 , Issue 1 , February 1982 , pp. 63 - 77
Copyright
Copyright © Cambridge University Press 1982

References

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