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The length of time required for a selectively neutral mutant to reach fixation through random frequency drift in a finite population*

Published online by Cambridge University Press:  14 April 2009

Motoo Kimura
Affiliation:
National Institute of Genetics, Mishima, Japan
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Frequency distribution of the length of time until fixation (excluding the cases of eventual loss) of a selectively neutral mutant in a finite population was obtained. With 4Ne generations (Ne, effective population size) as the unit length of time, the distribution has mean μ1 = 1, standard deviation σ = 0·538, skewness γ1 = 1·67 and kurtosis γ2 = 4·51 (see Fig. 1).

Type
Short Papers
Copyright
Copyright © Cambridge University Press 1970

References

REFERENCES

Kimura, M. (1955). Solution of a process of random genetic drift with a continuous model. Proc. Natn. Acad. Sci., U.S.A. 41, 144150.Google Scholar
Kimura, M. & Chow, J. F. (1963). The measurement of effective population number. Evolution 17, 279288.Google Scholar
Kimura, M. & Ohta, T. (1969 a). The average number of generations until fixation of a mutant gene in a finite population. Genetics, Princeton 61, 763771.CrossRefGoogle Scholar
Kimura, M. & Ohta, T. (1969 b). The average number of generations until extinction of an individual mutant gene in a finite population. Genetics, Princeton (in the Press).CrossRefGoogle Scholar
Narain, P. (1969). A note on the diffusion approximation for the variance of the number of generations until fixation of a neutral mutant gene. Genet. Res., Camb. (in the Press).Google Scholar