Hostname: page-component-586b7cd67f-tf8b9 Total loading time: 0 Render date: 2024-11-23T08:31:05.904Z Has data issue: false hasContentIssue false
  • English
  • Français

Hybrid dysgenesis in Drosophila melanogaster: synthesis of RP strains by chromosomal contamination

Published online by Cambridge University Press:  14 April 2009

Margaret G. Kidwell  and
Helen M. Sang
Margaret G. Kidwell
Affiliation:
Division of Biology and Medicine, Brown University, Providence, Rhode Island 02912, U.S.A.
Helen M. Sang
Affiliation:
Department of Molecular Biology, University of Edinburgh, Kings Buildings, Edinburgh EH9 3JR, Scotland
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Several strains have been synthesized which have reactive (R) properties in the I–R system of hybrid dysgenesis and which are also classified as active P strains in the P–M system. The synthesis of this previously unknown combination of types was accomplished by employing a mating scheme which allowed transposition (chromosomal contamination) of P, but not I, factors from IP to RM chromosomes in dysgenic F1 males. The successful synthesis of RP strains provides strong evidence that the apparent absence of this combination in natural and laboratory populations of melanogaster is not due to a biological incompatibility between these two types.

Type
Research Article
Information
Genetics Research , Volume 47 , Issue 3 , June 1986 , pp. 181 - 185
Copyright
Copyright © Cambridge University Press 1986

References

Bingham, P. M., Kidwell, M. G. & Rubin, G. M. (1982). The molecular basis of P–M hybrid dysgenesis: the role of the P element, a P-strain-specific transposon family. Cell 29, 995–1004.CrossRefGoogle Scholar
Bregliano, J. C. & Kidwell, M. G. (1983). Hybrid dysgenesis determinants. In Mobile Genetic Elements (ed. Shapiro, J. A.), pp. 363–410. New York: Academic Press.Google Scholar
Bregliano, J. C., Picard, G., Bucheton, A., Pelisson, A., Lavige, J. G. & L'Heritier, P. (1980). Hybrid dysgenesis in Drosophila melanogaster. Science 207, 606–611.CrossRefGoogle ScholarPubMed
Bucheton, A. & Picard, G. (1978). Non-Mendelian female sterility in Drosophila melanogaster: hereditary transmission of reactivity levels. Heredity 40, 207–223.CrossRefGoogle Scholar
Bucheton, A., Paro, R., Sang, H. M., Pelisson, A. & Finnegan, D. J. (1984). The molecular basis of I–R hybrid dysgenesis in Drosophila melanogaster: identification, cloning, and properties of the I factor. Cell 38, 153–163.CrossRefGoogle ScholarPubMed
Engels, W. R. (1979). Hybrid dysgenesis in Drosophila melanogaster: rules of inheritance of female sterility. Genetical Research 33, 219–236.CrossRefGoogle Scholar
Engels, W. R. & Preston, C. R. (1979). Hybrid dysgenesis in Drosophila melanogaster: the biology of female and male sterility. Genetics 92, 161–174.CrossRefGoogle ScholarPubMed
Kidwell, M. G. (1979). Hybrid dysgenesis in Drosophila melanogaster: the relationship between the P–M and I–R interaction systems. Genetical Research 33, 205–217.CrossRefGoogle Scholar
Kidwell, M. G. (1983). Evolution of hybrid dysgenesis determinants in Drosophila melanogaster. Proceedings of the National Academy of Sciences (U.S.A.) 80, 1655–1659.CrossRefGoogle ScholarPubMed
Kidwell, M. G. (1984). Hybrid dysgenesis in Drosophila melanogaster: partial sterility associated with embryo lethality in the P–M system. Genetical Research 44, 11–28.CrossRefGoogle ScholarPubMed
Kidwell, M. G. (1985). Hybrid dysgenesis in Drosophila melanogaster: nature and inheritance of P element regulation. Genetics 111, 337–350.CrossRefGoogle ScholarPubMed
Kidwell, M. G., Kidwell, J. F. & Sved, J. A. (1977). Hybrid dysgenesis in Drosophila melanogaster: a syndrome of aberrant traits including mutation, sterility and male recombination. Genetics 86, 813–833.CrossRefGoogle ScholarPubMed
Kidwell, M. G., Frydryk, T. & Novy, J. B. (1983). The hybrid dysgenesis potential of Drosophila melanogaster strains of diverse temporal and geographicalnaturalorigins. Drosophila Information Service 59, 63–69.Google Scholar
Lindsley, D. L. & Grell, E. H. (1968). Genetic variations of Drosophila melanogaster. Carnegie Institution of Washington Publication no. 627.Google Scholar
O'Hare, K. & Rubin, G. M. (1983). Structure of P transposable elements of Drosophila melanogaster and their sites of insertion and excision. Cell 34, 25–35.CrossRefGoogle ScholarPubMed
Picard, G. (1976). Non-mendelian female sterility in Drosophila melanogaster: hereditary transmission of I factor. Genetics 83, 107–123.CrossRefGoogle ScholarPubMed
Rubin, G. M., Kidwell, M. G. & Bingham, P. M. (1982). The molecular basis of P–M hybrid dysgenesis: the nature of induced mutations. Cell, 29, 987–994.CrossRefGoogle ScholarPubMed
Schaefer, R. E., Kidwell, M. G. & Fausto-Sterling, A. (1979). Hybrid dysgenesis in Drosophila melanogaster; morphological and cytological studies of ovarian dysgenesis. Genetics 92, 1141–1152.CrossRefGoogle ScholarPubMed