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Hybrid dysgenesis in Drosophila melanogaster: partial sterility associated with embryo lethality in the P-M system

Published online by Cambridge University Press:  14 April 2009

Margaret G. Kidwell
Margaret G. Kidwell
Affiliation:
Division of Biology and Medicine, Brown University, Providence, Rhode Island 02912, U.S.A.
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Variable frequencies of unhatched eggs were observed to be produced by a number of F1 interstrain hybrids. This type of partial sterility resulting from F2 embryo death was found to be associated with the P-M system of hybrid dysgenesis. Dysgenic hybrid progeny of crosses between M strain females and P strain males may therefore have reduced fertility due to the disruption of development at two different stages: early F1 gonadal development and early F2 embryo development. These disruptions result in the previously described F1 gonadal dysgenesis (GD sterility) and F2 embryo lethality (EL sterility) respectively. The two morphologically distinct types of P-M-associated sterility differ in their patterns of response to F1 developmental temperature, and the temperature-sensitive period for EL sterility occurs considerably later in F1 development than for GD sterility. EL sterility is similar to SF sterility, which is associated with the I–R system of hybrid dysgenesis in that both result from death during early F2 embryogenesis. However, EL sterility differs from SF sterility in not being restricted to hybrids of the female sex and in showing different patterns of response to temperature and ageing in the F1 generation. Some implications of the existence of EL sterility for methods of strain classification in the I–R system are explored.

Type
Research Article
Information
Genetics Research , Volume 44 , Issue 1 , August 1984 , pp. 11 - 28
Copyright
Copyright © Cambridge University Press 1984

References

REFERENCES

Bingham, P. M., Kidwell, M. G. & Rubin, G. M. (1982). The molecular basis of P-M hybrid dysgenesis: the role of the P element, a P-strain-specific transposon family. Cell 29, 995–1004.CrossRefGoogle Scholar
Bodenstein, D. (1950). The postembryonic development of Drosophila. In Biology of Drosophila (ed. Demerec, M.), pp. 275–367. New York: Wiley.Google Scholar
Bregliano, J. C. & Kidwell, M. G. (1983). Hybrid dysgenesis determinants. In Mobile Genetic Elements (ed. Shapiro, J. A.), pp. 363–410. New York, London, San Francisco: Academic Press.Google Scholar
Bregliano, J. C., Picard, G., Bucheton, A., Pelisson, A., Lavige, J. M. & L'Héritier, P. (1980). Hybrid dysgenesis in Drosophila melanogaster. Science 207, 606–611.CrossRefGoogle ScholarPubMed
Broadhead, R. S., Kidwell, J. F. & Kidwell, M. G. (1977). Variation of the recombination fraction in Drosophila melanogaster females. Journal of Heredity 68, 323–326.CrossRefGoogle ScholarPubMed
Bucheton, A. (1979). Non-Mendelian female sterility in Drosophila melanogaster: influence of ageing and thermic treatments. II. Action of thermic treatments on the sterility of SF females and the reactivity of reactive females. Biologic Cellulaire 34, 43–50.Google Scholar
Bucheton, A., Lavige, J. M., Picard, G. & L'Héritier, Ph. (1976). Non-Mendelian female sterility in Drosophila melanogaster: quantitative variations in the efficiency of inducer and reactive strains. Heredity 36, 305–314.CrossRefGoogle ScholarPubMed
Eggleston, P. & Kearsey, M. M. (1980). Hybrid dysgenesis in Drosophila: correlation between dysgenic traits. Heredity 44, 237–249.CrossRefGoogle ScholarPubMed
Engels, W. R. (1979). Hybrid dysgenesis in Drosophila melanogaster: rules of inheritance of female sterility. Genetical Research 33, 219–236.CrossRefGoogle Scholar
Engels, W. R. (1981). Hybrid dysgenesis in Drosophila and the stochastic loss hypothesis. Cold Spring Harbor Symposium of Quantitative Biology 45, 561–565.CrossRefGoogle ScholarPubMed
Engels, W. R. (1983). The P family of transposable elements in Drosophila. Annual Review of Genetics 17, 315–344.CrossRefGoogle Scholar
Engels, W. R. & Preston, C. R. (1979). Hybrid dysgenesis in Drosophila melanogaster: the biology of female and male sterility. Genetics 92, 161–174.CrossRefGoogle ScholarPubMed
Finnegan, D. J., Bucheton, A. & Sang, H. M. (1983). The molecular basis of hybrid dysgenesis in Drosophila melanogaster. In Genetic Rearrangement (ed. Chater, K. F., Cullis, C. A., Hopwood, D. A., Johnston, A. W. B. and Woolhouse, H. W.), pp. 75–92. Sunderland, Mass: Sinauer.Google Scholar
Kidwell, M. G. (1979). Hybrid dysgenesis in Drosophila melanogaster: the relationship between the P-M and I-R interaction systems. Genetical Research 33, 205–217.CrossRefGoogle Scholar
Kidwell, M. G. (1983 a). EL sterility: a second type of partial sterility associated with the P-M system of hybrid dysgenesis in Drosophila melanogaster. Genetics 104, s42.Google Scholar
Kidwell, M. G. (1983 b). Evolution of hybrid dysgenesis determinants in Drosophila melanogaster. Proceedings of the National Academy of Science (USA) 80, 1655–1659.CrossRefGoogle ScholarPubMed
Kidwell, M. G. & Novy, J. B. (1979). Hybrid dysgenesis in Drosophila melanogaster: sterility resulting from gonadal dysgenesis in the P-M system. Genetics 92, 1127–1140.CrossRefGoogle ScholarPubMed
Kidwell, M. G., Frydryk, T. & Novy, J. B. (1983). The hybrid dysgenesis potential of Drosophila melanogaster strains of diverse temporal and geographical origin. Drosophila Information Service 59, 63–69.Google Scholar
Kidwell, M. G., Kidwell, J. F. & Sved, J. A. (1977). Hybrid dysgenesis in Drosophila melanogaster: a syndrome of aberrant traits including mutation, sterility and male recombination. Genetics 86, 813–833.CrossRefGoogle ScholarPubMed
Lavige, J. M. & Lecher, P. (1982). Mitoses anormales dans les embryons à développement bloqué dans le systéme I-R de dysgénèsie hybride chez Drosophila melanogaster. Biologie Cellulaire 44, 9–14.Google Scholar
Minato, K. (1979). Analysis of the decreased hatchability of eggs laid by flies reared on excess yeast in Drosophila melanogaster. Annual Report of the National Institute of Genetics, Japan, no. 30.Google Scholar
Picard, G., Lavige, J. M., Bucheton, A. & Bregliano, J. C. (1977). Non-Mendelian female sterility in Drosophila melanogaster: physiological pattern of embryo lethality. Biologic Cellulaire 29, 89–98.Google Scholar
Robertson, F. W. & Sang, J. H. (1944). The ecological determinants of population growth in a Drosophila culture. II. Circumstances affecting egg viability. Proceedings of the Royal Society of London B 132, 277–291.Google Scholar
Rubin, G. M., Kidwell, M. G. & Bingham, P. M. (1982). The molecular basis of P-M hybrid dysgenesis: the nature of induced mutations. Cell 29, 987–994.CrossRefGoogle ScholarPubMed
Schaefer, R. E., Kidwell, M. G. & Fausto-Sterling, A. (1979). Hybrid dysgenesis in Drosophila melanogaster: morphological and cytological studies of ovarian dysgenesis. Genetics 92, 1141–1152.CrossRefGoogle ScholarPubMed