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Genetical studies on the skeleton of the mouse XXVII. The Development of oligosyndactylism

Published online by Cambridge University Press:  14 April 2009

Hans Grüneberg
Hans Grüneberg
Affiliation:
Experimental Genetics Research Unit (Medical Research Council), University College London
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The complex anatomy of the adult limb skeleton of Os/+ mice is attributable to a reduction of the preaxial margin of the foot plates. This is detectable, in the fore limbs, in the 11-day stage, i.e. before condensations of mesenchyme have taken place. The involvement of the skeleton is thus secondary to an earlier defect in the foot plates. The cause of the latter has not been discovered.

Type
Research Article
Information
Genetics Research , Volume 2 , Issue 1 , February 1961 , pp. 33 - 42
Copyright
Copyright © Cambridge University Press 1961

References

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