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The genetic variability of polygenic characters under optimizing selection, mutation and drift

Published online by Cambridge University Press:  14 April 2009

M. G. Bulmer
M. G. Bulmer
Affiliation:
Department of Biomathematics, University of Oxford
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Summary

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The effect of optimizing selection, mutation and drift on a metric character determined by a large number of loci with equal effects without dominance was investigated theoretically. Conditions for a stable equilibrium under selection and mutation, in the absence of drift, have been obtained, and hence the amount of genetic variability which can be maintained by mutation has been determined. An approximate expression for the average amount of genetic variability to be expected in the presence of drift in a population of finite size has also been obtained and evaluated.

Type
Research Article
Information
Genetics Research , Volume 19 , Issue 1 , February 1972 , pp. 17 - 25
Copyright
Copyright © Cambridge University Press 1972

References

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