Hostname: page-component-586b7cd67f-rdxmf Total loading time: 0 Render date: 2024-11-20T09:31:02.110Z Has data issue: false hasContentIssue false
  • English
  • Français

Genetic studies on nucleolus organizer regions (NORs) in cattle

Published online by Cambridge University Press:  14 April 2009

B. Mayr ,
K. Gruber ,
G. Brem  and
G. Mayrhofer
B. Mayr
Affiliation:
Institute for Animal Breeding and Genetics, Veterinary University, Vienna, Austria
K. Gruber
Affiliation:
Ludwig Bollzmann Institute for Immuno- and Cytogenetic Research, Vienna, Austria
G. Brem
Affiliation:
Institute for Animal Breeding and Care, Ludwig Maximilian University, Munich, FRG
G. Mayrhofer
Affiliation:
Institute for Animal Breeding and Genetics, Veterinary University, Vienna, Austria
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Experimentally produced monozygotic twins, natural opposite sex blood chimeras (freemartins), and several pedigrees were used to evaluate the genetic influences on the nucleolus organizer region (NOR) patterns in cattle. In monozygotic twins, the NOR patterns of both twins are extremely similar. In chimeras, NOR patterns of genetically identical, peripheral blood lymphocytes (PBL) from the two partners resemble each other. In contrast, genetically different PBL (sib organ) differ significantly in the same environment. A high heritability of the individual NOR patterns is also demonstrated in our 23 pedigrees. In conclusion, our data demonstrate that variation in NOR expression is predominantly due to genetic factors.

Type
Research Article
Information
Genetics Research , Volume 53 , Issue 2 , April 1989 , pp. 111 - 118
Copyright
Copyright © Cambridge University Press 1989

References

Busch, H., Lischwe, M., Michalik, J., Chan, P.-K. & Busch, R. K. (1982). Nucleolar proteins of special interest: silver staining proteins B23 and C23 and antigens of human tumour nucleoli. In: The Nucleolus (ed. Jordan, E. G. and Cullis, C. A.), Cambridge University Press.Google Scholar
Di Berardino, D. E., Arrighi, F. E. & Kieffer, M. N. (1979). Nucleolus organizer regions in two species of Bovidae. Journal of Heredity 70, 47–50.CrossRefGoogle ScholarPubMed
Goodpasture, C. & Bloom, S. E. (1975). Visualisation of nucleolus organizer regions in mammalian chromosomes using silver staining. Chromosoma 55, 37–50.CrossRefGoogle Scholar
Henderson, L. M. & Bruére, N. (1979). Conservation of nucleolus organizer regions during evolution in sheep, goat, cattle, and audad. Canadian Journal of Genetics and Cytology 21, 1–8.CrossRefGoogle Scholar
Howell, W. M. (1977). Visualisation of ribosomal gene activity: silver stains proteins associated with rRNA transcribed from oocyte chromosomes. Chromosoma 62, 361–367.CrossRefGoogle ScholarPubMed
Howell, W. M. & Black, D. A. (1980). Controlled silver staining of nucleolus organizer regions with a protective colloidal developer: a 1 step method. Experientia 36, 1014–1015.CrossRefGoogle ScholarPubMed
Howell, W. M., Denton, T. E. & Diamond, J. R. (1975). Differential staining of the satellite regions of human acrocentric chromosomes. Experientia 31, 260–262.CrossRefGoogle ScholarPubMed
Markovic, V. D., Worton, R. G. & Berg, J. M. (1978). Evidence for the inheritance of silver-stained nucleolus organizer regions. Human Genetics 41, 181–187.CrossRefGoogle ScholarPubMed
Mayr, B. & Czaker, R. (1981). Variable position of nucleolus organizer regions in Bovidae. Experientia 37, 564–565.CrossRefGoogle ScholarPubMed
Mayr, B., Schleger, W. & Auer, H. (1987). Frequencies of Ag-NORs in cattle. Journal of Heredity 78, 206–207.CrossRefGoogle Scholar
Mikelsaar, A. V., Schwarzacher, H. G., Schnedl, W. & Wagenbichler, P. (1977). Inheritance of Ag-stainability of nucleolus organizer regions. Investigations in seven families with trisomy 21. Human Genetics 38, 183–188.CrossRefGoogle ScholarPubMed
Miller, O. J., Miller, D. A., Dev, V. G., Tantravahi, R. & Croce, R. M. (1976). Expression of human, and suppression of mouse nucleolus organizer activity in mouse-human somatic cell hybrids. Proceedings of the National Academy of Sciences of the USA 73, 4531–4535.CrossRefGoogle ScholarPubMed
Morton, C. C., Corey, L. A., Nance, W. E. & Brown, J. A. (1981). Quinacrine mustard and nucleolar organizer region heteromorphisms in twins. Acta Geneticae Medicae et Gemellologicae 30, 39–49.CrossRefGoogle ScholarPubMed
Reading Conference (1980). Proceedings of the 1st International Conference for Standardization of Banded Karyotypes of Domestic Animals. Hereditas 92, 145–162.Google Scholar
Weltens, R., Kirsch-Volders, M., Hens, L., Defrisse-Gussenhoven, E. & Susanne, C. (1985). NOR variability in twins. Acta Genetica et Gemellologica 34, 141–151.Google ScholarPubMed
Zakharov, A. F., Davudov, A. Z., Benjush, V. A. & Egolina, N. (1982). Genetic determination of NOR activity in human lymphocytes from twins. Human Genetics 60, 24–29.CrossRefGoogle ScholarPubMed