Hostname: page-component-586b7cd67f-dsjbd Total loading time: 0 Render date: 2024-11-26T14:01:59.119Z Has data issue: false hasContentIssue false
  • English
  • Français

Genetic control of recombination and the incompatibility system in Schizophyllum commune

Published online by Cambridge University Press:  14 April 2009

G. Simchen
G. Simchen
Affiliation:
Department of Genetics, The University, Birmingham 15
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Crossing-over between the α and the β loci constituting the A incompatibility factor gives rise to two new specificities which are compatible with both parental As and with each other. The frequency of monokaryotic mycelia carrying re-combinant A factors is shown to be under genotypic control in a multiple crosses programme (6 × 6), selection for high and low recombination frequencies (two generations), and crosses between the selection lines. The recombination values based on samples of 100 monokaryons, range from 0 to 21%; however, the more accurately estimated values of the ‘High’ and ‘Low’ selections are 14% and 4%, each being based on approximately 2,000 mycelia.

The data are compatible with a gene-system consisting of the postulated locus rec which has a major effect on recombination and which is linked to the A factor, and several minor effects by other loci. Alternative interpretations are presented and discussed. The apparent dominance of low frequencies of recombination on high frequencies can be related to the breeding behaviour of S. commune. Thus close linkage between α and β allows a high number of A specificities to be maintained in a population as well as high out-breeding potential, while the inbreeding potential (i.e. dikaryotic combinations between monokaryons originating from a single fruit-body) is kept low and near its minimum.

The significance of the two-locus structure of the incompatibility factors is examined theoretically in an Appendix at the end of the Discussion section.

Type
Research Article
Information
Genetics Research , Volume 9 , Issue 2 , April 1967 , pp. 195 - 210
Copyright
Copyright © Cambridge University Press 1967

References

REFERENCES

Bartlett, M. S. (1947). The use of transformation. Biometrics 3, 39–52.CrossRefGoogle Scholar
Bodmer, W. F. & Parsons, P. A. (1962). Linkage and recombination in evolution. Adv. Genet. 11, 1–100.CrossRefGoogle Scholar
Day, P. R. (1960). The structure of the A mating type locus in Coprinus lagopus. Genetics, 45, 641–650.CrossRefGoogle ScholarPubMed
Day, P. R. (1963). The structure of the A mating type factor in Coprinus lagopus: wild alleles. Genet. Bes. 4, 323–325.Google Scholar
Day, P. R. & Anderson, G. E. (1961). Two linkage groups in Coprinus lagopus. Genet. Res. 2, 414–423.CrossRefGoogle Scholar
Day, P. R. & Holliday, R. (1959). Incompatibility in Schizophyllum commune. Am. Nat. 93, 387–388.CrossRefGoogle Scholar
Ellingboe, A. H. (1963). Illegitimacy and specific factor transfer in Schizophyllum commune. Proc. natn. Acad. Sci., U.S.A. 49, 286–292.CrossRefGoogle ScholarPubMed
Ellingboe, A. H. (1965). Somatic recombination in Basidiomycetes. In Incompatibility in Fungi (Esser, K. & Raper, J. R., eds.), pp. 36–48. Berlin: Springer-Verlag.Google Scholar
Fisher, R. A. (1958). The Genetical Theory of Natural Selection, 2nd ed.New York: Dover.Google Scholar
Fisher, R. A. & Yates, F. (1963). Statistical Tables, 6th ed.Edinburgh and London: Oliver & Boyd.Google Scholar
Griffing, B. & Langridge, J. (1963). Factors affecting crossing-over in the tomato. Aust. J. biol. Sci. 16, 826–837.CrossRefGoogle Scholar
Griffiths, A. J. F. & Threlkeld, S. F. H. (1966). Internuclear effects on prototroph frequencies of some crosses in Neurospora crassa. Genetics, 54, 77–87.CrossRefGoogle ScholarPubMed
Jessop, A. P. & Catcheside, D. G. (1965). Interallelic recombination at the his-l locus in Neurospora crassa and its genetic control. Heredity, Lond. 20, 237–256.CrossRefGoogle Scholar
Koltin, Y., Raper, J. R. & Simchen, G. (1967). The genetic structure of the incompatibility factors of Schizophyllum commune: The B factor. Proc. natn. Acad. Sci. U.S.A. 57, 55–62.Google Scholar
Lavigne, S. & Frost, L. C. (1964). Recombination frequency and wild-type ancestry in linkage group I of Neurospora crassa. Genet. Res. 5, 366–378.CrossRefGoogle Scholar
Lawrence, M. J. (1963). The control of crossing-over in the X-chromosome of Drosophila melanogaster. Heredity, Lond. 18, 27–46.Google Scholar
Mather, K. (1942). Heterothally as an out-breeding mechanism in fungi. Nature, Lond. 149, 54–56.CrossRefGoogle Scholar
Mather, K. (1966). Variability and selection. Proc. R. Soc. B, 164, 328–340.Google ScholarPubMed
Papazian, H. P. (1951). The incompatibility factors and a related gene in Schizophyllum commune. Genetics, 36, 441–459.CrossRefGoogle Scholar
Raper, J. R., Baxter, M. G. & Middleton, R. B. (1958 a). The genetic structure of the incompatibility factors in Schizophyllum commune. Proc. natn. Acad. Sci. U.S.A. 44, 889–900.Google Scholar
Raper, J. R., Krongelb, G. S. & Baxter, M. G. (1958 b). The number and distribution of incompatibility factors in Schizophyllum. Am. Nat. 92, 221–232.Google Scholar
Raper, J. R., Baxter, M. G. & Ellingboe, A. H. (1960). The genetic structure of the incompatibility factors of Schizophyllum commune. The A factor. Proc. natn. Acad. Sci. U.S.A. 46, 833–842.CrossRefGoogle ScholarPubMed
Scott-Emuakpor, M. B. (1965). Genetic recombination in Neurospora crassa and N. sitophila. Genet. Res. 6, 216–225.CrossRefGoogle ScholarPubMed
Simchen, G. (1966). Monokaryotic variation and haploid selection in Schizophyllum commune. Heredity, Lond. 21, 241–263.CrossRefGoogle Scholar
Simchen, G. & Jinks, J. L. (1964). The determination of dikaryotic growth rate in the basidiomycete Schizophyllum commune: a biometrical analysis. Heredity, Lond. 19, 629–649.Google Scholar
Smith, B. R. (1965). Interallelic recombination at the his-5 locus in Neurospora crassa. Heredity, Lond. 20, 257–276.CrossRefGoogle ScholarPubMed
Smith, B. R. (1966). Genetic controls of recombination. I. The recombination-2 gene of Neurospora crassa. Heredity, Lond. 21, 481–498.CrossRefGoogle ScholarPubMed
Snider, P. J. & Raper, J. R. (1958). Nuclear migration in the basidiomycete Schizophyllum commune. Am. J. Bot. 45, 538–546.Google Scholar
Whitehouse, H. L. K. (1949). Heterothalism and sex in fungi. Biol. Rev. 24, 411–447.CrossRefGoogle Scholar