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Genetic control of flagellar structure in Chlamydomonas reinhardii

Published online by Cambridge University Press:  14 April 2009

J. R. Warr ,
A. McVittie ,
John Randall  and
J. M. Hopkins
J. R. Warr
Affiliation:
Department of Biophysics and Medical Research Council Biophysics Research Unit, University of London, King's College, 26–29 Drury Lane, London, W.C.2
A. McVittie
Affiliation:
Department of Biophysics and Medical Research Council Biophysics Research Unit, University of London, King's College, 26–29 Drury Lane, London, W.C.2
John Randall
Affiliation:
Department of Biophysics and Medical Research Council Biophysics Research Unit, University of London, King's College, 26–29 Drury Lane, London, W.C.2
J. M. Hopkins
Affiliation:
Department of Biophysics and Medical Research Council Biophysics Research Unit, University of London, King's College, 26–29 Drury Lane, London, W.C.2
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Seventeen non-motile strains of Chlamydomonas reinhardii isolated by Dr Lewin and thirty-six newly isolated strains have been examined in the electron microscope for structural abnormalities of the flagella. Fourteen of them have straight, paralysed flagella in which the central fibres are replaced by an irregular core of disorganized material. The fourteen mutations map at four unlinked loci. Some of them are leaky; light and electron microscope observations on leakiness are described. In the former case leakiness is measured by the proportion of motile cells, and in the latter by the proportion of intact centre fibres seen in transverse sections. The degree of leakiness is to some extent characteristic of particular loci.

A partial suppressor of some of these mutations has been isolated which acts on all the mutant alleles at two loci and to a much lesser extent on four out of five alleles at a third locus.

Type
Research Article
Information
Genetics Research , Volume 7 , Issue 3 , June 1966 , pp. 335 - 351
Copyright
Copyright © Cambridge University Press 1966

References

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