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Genetic analysis of the right (3′) end of the rosy locus in Drosophila melanogaster

Published online by Cambridge University Press:  14 April 2009

S. H. Clark ,
A. J. Hilliker  and
A. Chovnick
S. H. Clark
Affiliation:
Department of Molecular and Cell Biology, The University of Connecticut, Storrs, Connecticut 06268
A. J. Hilliker
Affiliation:
Department of Molecular and Cell Biology, The University of Connecticut, Storrs, Connecticut 06268
A. Chovnick
Affiliation:
Department of Molecular and Cell Biology, The University of Connecticut, Storrs, Connecticut 06268
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Prior reports from this laboratory have described the experimental basis for our understanding of the rosy locus (ry: 3–52·0) of Drosophila melanogaster as a bipartite genetic entity consisting of a structural element that codes for the xanthine dehydrogenase (XDH) peptide and a contiguous cis-acting control element immediately to the left of the structural element. Although the left end (5′) of the structural element has been well defined, the right boundary (3′) has been given only casual treatment in our prior reports. In our recent studies of rosy locus expression we have been concerned with the production and identification of mutations in the non-structural regions immediately flanking the structural element. An improved definition of the right end of the structural element is essential to this analysis. In addition to producing a better definition of the right boundary of the structural element, this study produced several phenotypically novel mutations. These mutations were classified initially ascontrol element mutations, but upon analysis were found to map within the rosy structural element. No evidence was obtained for the existence of a control element contiguous with the right end of the structural element.

Type
Research Article
Information
Genetics Research , Volume 47 , Issue 2 , April 1986 , pp. 109 - 116
Copyright
Copyright © Cambridge University Press 1986

References

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