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Evidence that Linkage Group IV as well as Linkage Group X of the mouse are in chromosome 10*

Published online by Cambridge University Press:  14 April 2009

N. L. A. Cacheiro
Affiliation:
Biology Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37830, USA
Liane B. Russell
Affiliation:
Biology Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37830, USA
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Summary

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Four translocations in which one breakpoint was known to be at or closely linked to the LGIV marker Steel, Sl, were studied in an attempt to identify cytologically the as yet unassigned Linkage Group IV of the mouse. The cytological results indicate that chromosome 10, which had previously been matched with LGX, is involved in each of the four translocations, the break being in 10D. Recombination between Sl and the LGX marker grizzled, gr, was determined to be 6–14%. The combined cytological and genetic results indicate that LGIV and LGX are both in chromosome 10, and that the order may be centromere-gr-Sl.

Type
Short Papers
Copyright
Copyright © Cambridge University Press 1975

References

REFERENCES

Cacheiro, N. L. & Russell, L. B. (1974). Possibility that Sl is in chromosome 10. Mouse News Letter 50, 52.Google Scholar
Committee on Standardized Genetic Nomenclature in Mice. (1972). Standard karyotype of the mouse, Mus musculus. Journal of Heredity 63, 6972.Google Scholar
Dev, V. G., Miller, D. A., Charen, J. & Miller, O. J. (1974). Translocation of centromeric heterochromatin in the T(10;13)199H stock of Mus musculus and localization of chromosome breakpoints. Cytogenetics and Cell Genetics 13, 256267.Google Scholar
Green, M. C. (1966). Mutant genes and linkages. In Biology of the Laboratory Mouse (Ed. Green, E. L.), pp. 87150. New York: McGraw-Hill.Google Scholar
Miller, O. J., Miller, D. A., Kouri, R. E., Allderdice, P. W., Dev, V. G., Grewal, M. S. & Hutton, J. J. (1971 a). Identification of the mouse karyotype by quinacrine fluorescence, and tentative assignment of seven linkage groups. Proceedings of the National Academy of Sciences 68, 15301533.CrossRefGoogle ScholarPubMed
Miller, O. J., Miller, D. A., Kouri, R. E., Dev, V. G., Grewal, M. S. & Hutton, J. J. (1971 b). Assignment of linkage groups VIII and X to chromosomes in Mus musculus and identification of the centromeric end of linkage group I. Cytogenetics 10, 452464.Google Scholar
Mouse News Letter. (1974). Linkage map of the mouse. 51, 7.Google Scholar
Nesbitt, M. N. & Francke, U. (1973). A system of nomenclature for band patterns of mouse chromosomes. Chromosoma 41, 145158.CrossRefGoogle ScholarPubMed
Russell, L. B. (1972). Unnamed mutants that have arisen at Oak Ridge (all stocks of independent origin). Mouse News Letter 47, 60.Google Scholar
Russell, L. B. & Cacheiro, N. L. (1975). Superimposition of linkage groups X and IV. Mouse News Letter 52, 4647.Google Scholar
Sarvella, P. A. & Russell, L. B. (1956). Steel, a new dominant gene in the house mouse. Journal of Heredity 47, 123128.CrossRefGoogle Scholar
Wickham, L. & Weaver, S. J. (1963). Mouse News Letter 29, 72.Google Scholar