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Erythrocytic antigenic differences between individuals of the deer mouse, Peromyscus maniculatus*

Published online by Cambridge University Press:  14 April 2009

David I. Rasmussen
David I. Rasmussen
Affiliation:
Mammalian Genetics Center, Department of Zoology, University of Michigan, Ann Arbor, Michigan

Extract

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1. Antigenic polymorphism between individuals of the subspecies Peromyscus maniculatus gracilis is demonstrated.

2. Absorption analysis of heteroimmune rabbit sera using erythrocytes of individual mice revealed two unitary complete (saline) agglutinins, designated as anti-A and anti-B, reactive to erythrocytic antigens in this species.

Isoimmunization apparently demonstrated these same antigenic differences.

3. The two antigenic characters (A and B) defined by the agglutinins are inherited as if simply related to allelic factors designated PmA and PmB respectively.

4. These two antigens are found in representatives of both the subspecies P. m. gracilis and P. m. bairdii, and, in addition, the A antigen was observed in a laboratory stock of P. polionotus. Tested individuals of the species P. leucopus and Mus musculus, however, possessed neither antigen, and samples of human blood also lacked both antigens.

5. Species-specific agglutinins distinguishing individuals of the species P. leucopus and P. maniculatus, and population-specific agglutinins which distinguished between individuals of the subspecies P. m. bairdii and P. m. gracilis, have been observed.

Type
Research Article
Information
Genetics Research , Volume 2 , Issue 3 , November 1961 , pp. 449 - 455
Copyright
Copyright © Cambridge University Press 1961

References

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