Hostname: page-component-586b7cd67f-r5fsc Total loading time: 0 Render date: 2024-11-23T01:28:30.005Z Has data issue: false hasContentIssue false
  • English
  • Français

Embryonic bone growth in lines of mice selected for large and small body size

Published online by Cambridge University Press:  14 April 2009

Ann Blakley
Ann Blakley
Affiliation:
Institute of Animal Genetics, West Mains Road, Edinburgh EH9 3JN, Scotland
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Embryonic tibia growth was measured in large, small and control mouse embryos in situ and in organ culture. In situ tibias of the large line were longer than controls which were longer than tibias of the small line. Relative growth was approximately equal among lines. In culture tibias of the small line grew more than controls and as much as or more than tibias of the large line. Embryonic genotype appears to be more important in regulating tibia growth than uterine environment. Humoral differences among lines may influence tibia growth.

Type
Research Article
Information
Genetics Research , Volume 34 , Issue 2 , October 1979 , pp. 77 - 85
Copyright
Copyright © Cambridge University Press 1979

References

REFERENCES

Aitken, R. J., Bowman, P. & Gauld, I. (1977). The effect of synchronous and asynchronous egg transfer on foetal weight in mice selected for large and small body size. Journal of Embryology and Experimental Morphology 37, 59–64.Google ScholarPubMed
Aydelotte, M. B. & Kochhar, D. M. (1972). Development of mouse limb buds in organ culture: Chondrogenesis in the presence of a proline analog, L-azetidine-2-Carboxlic acid. Developmental Biology 28, 191–201.CrossRefGoogle ScholarPubMed
Biggers, J. D., Gwatkin, R. B. L. & Heyner, S. (1961). Growth of embryonic avian and mammalian tibiae on a relatively simple chemically defined medium. Erperimental Cell Research 25, 41–58.CrossRefGoogle ScholarPubMed
Bowman, P. & McLaren, A. (1970). Cell number in early embryos from strains of mice selected for large and small body size. Genetical Research 15, 261–263.CrossRefGoogle ScholarPubMed
Falconer, D. S. (1973). Replicated selection for body size in mice. Genetical Research 22, 291–321.CrossRefGoogle ScholarPubMed
Kochhar, D. M. & Aydelotte, M. B. (1974). Susceptible stages and abnormal morphogenesis in the developing mouse limb, analysed in organ culture after transplacental exposure to vitamin A (retinoic acid). Journal of Embryology and Experimental Morphology 31, 721–734.Google ScholarPubMed
Paul, J. (1965). Cell and Tissue Culture, 3rd ed.Edinburgh and London: E. S. Livingstone.Google Scholar
Theiler, K. (1972). The House Mouse. Berlin: Springer-Verlag.Google Scholar