Hostname: page-component-586b7cd67f-r5fsc Total loading time: 0 Render date: 2024-11-26T15:09:19.931Z Has data issue: false hasContentIssue false
  • English
  • Français

Effects of selection for independent changes in two highly correlated body weight traits of mice*

Published online by Cambridge University Press:  14 April 2009

J. C. McCarthy  and
D. P. Doolittle
J. C. McCarthy
Affiliation:
Faculty of Agriculture, University College, Glasnevin, Dublin 9, Ireland and Purdue University, Lafayette, Indiana 47907, U.S.A.
D. P. Doolittle
Affiliation:
Faculty of Agriculture, University College, Glasnevin, Dublin 9, Ireland and Purdue University, Lafayette, Indiana 47907, U.S.A.
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Mice were selected for high and low body weight at 5 and at 10 weeks of age. Selection was performed (1) separately for each trait, and (2) for various combinations of the two traits, using (a) independent culling levels and (b) restricted indices. Two-way selection for each trait separately gave large responses and correlated responses. Selection by independent culling levels intended to increase 5-week weight while restricting change in 10-week weight gave no demonstrable response; selection by culling levels intended to decrease 5-week weight while restricting change in 10-week weight resulted in decreases in body weights at both ages. Index selection, intended to change weight at one age while holding that at the other age constant, was generally successful. Observed responses did not conform very well with predicted responses for either index or culling levels selection. The significance of these observations in regard to the problem of selection involving restriction of traits is discussed.

Type
Research Article
Information
Genetics Research , Volume 29 , Issue 2 , April 1977 , pp. 133 - 145
Copyright
Copyright © Cambridge University Press 1977

References

REFERENCES

Abplanalp, H., Ogasawaba, F. X. & Asmundson, V. S. (1963). Influence of selection for body weight at different ages on growth of turkeys. British Poultry Science 4, 71–82.CrossRefGoogle Scholar
Bell, A. E. & Burris, M. J. (1973). Simultaneous selection for two correlated traits in Tribolium. Genetical Research 21, 29–46.CrossRefGoogle Scholar
Bohren, B. B., Hill, W. G. & Robertson, A. (1966). Some observations on asymmetrical correlated responses to selection. Genetical Research 7, 44–57.CrossRefGoogle ScholarPubMed
Falconer, D. S. (1960). Introduction to Quantitative Genetics, pp. 238–239. Edinburgh: Oliver and Boyd.Google Scholar
Falconer, D. S. (1973). Replicated selection for body weight in mice. Genetical Research 22, 291–321.CrossRefGoogle ScholarPubMed
Hill, W. G. (1972). Estimation of realised heritabilities from selection experiments. I: Divergent selection II: Selection in one direction. Biometrics 28, 747–780.CrossRefGoogle Scholar
McCarthy, J. C. (1967). The effects of inbreeding on the components of litter size in mice. Genetical Research 10, 73–80.CrossRefGoogle ScholarPubMed
Okada, I. & Hardin, R. T. (1967). An experimental examination of restricted selection index using Tribolium castaneum. I. The results of two-way selection. Genetics 57, 227–236.CrossRefGoogle ScholarPubMed
Okada, I. & Hardin, R. T. (1970). An experimental examination of restricted selection index using Tribolium castaneum. II. The results of long-term one-way selection. Genetics 64, 533–539.CrossRefGoogle ScholarPubMed
Rutledge, J. J., Eisen, E. J. & Legates, J. E. (1973). An experimental evaluation of genetic correlation. Genetics 75, 709–726.CrossRefGoogle ScholarPubMed
Schelnberg, E., Bell, A. E. & Anderson, V. L. (1967). Genetic gains in populations of Tribolium castaneum under uni-stage tandem selection and under restricted selection indices. Genetics 55, 69–90.CrossRefGoogle Scholar