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Effects of autosomal inversions on meiotic exchange in distal and proximal regions of the X chromosome in a natural population of Drosophila melanogaster

Published online by Cambridge University Press:  14 April 2009

Paul D. Sniegowski ,
Anne Pringle  and
Kimberly A. Hughes
Paul D. Sniegowski*
Affiliation:
Department of Ecology and Evolution, University of Chicago, 1101 E. 57th St. Chicago, Illinois 60637 USA
Anne Pringle
Affiliation:
Department of Ecology and Evolution, University of Chicago, 1101 E. 57th St. Chicago, Illinois 60637 USA
Kimberly A. Hughes
Affiliation:
Department of Ecology and Evolution, University of Chicago, 1101 E. 57th St. Chicago, Illinois 60637 USA
*
*Current address: Center for Microbial Ecology, Michigan State University, East Lansing, MI 48824 USA
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We have investigated the interchromosomal effect of the naturally-occurring paracentric inversions In(2L)t and In(3R)P on meiotic recombination in two regions of the X chromosome in Drosophila melanogaster. Previous authors have suggested that the rate of recombination at the tip of the X chromosome may be substantially higher in some natural populations than values measured in the laboratory, due to the interchromosomal effect of heterozygous autosomal inversions. This suggestion was motivated by observations that transposable elements are not as common at the tip of the X chromosome as predicted by recent research relating reduced meiotic exchange to increased element abundance in D. melanogaster. We examined the effects of heterozygous In(2L)t and In(3R)P on recombination at both the tip and base of the X chromosome on a background of isogenic major chromosomes from a natural population. Both inversions substantially increased the rate of recombination at the base; neither one affected recombination at the tip. The results suggest that the presence of inversions in the study population does not elevate rates of crossing over at the tip of the X chromosome. The relevance of these results to ideas relating transposable element abundance to recombination rates is discussed.

Type
Research Article
Information
Genetics Research , Volume 63 , Issue 1 , February 1994 , pp. 57 - 62
Copyright
Copyright © Cambridge University Press 1994

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