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The effect of various physiological conditions on host-controlled restriction in Escherichia coli K(P1)

Published online by Cambridge University Press:  14 April 2009

J. Schell
Affiliation:
Laboratory for Microbiology, State University Ghent, Belgium
S. W. Glover
Affiliation:
M.R.C. Microbial Genetics Research Unit Hammersmith Hospital, Ducane Road, London, W.12
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Growth of K(P1) bacteria under conditions which lead to a reduction in the level of nucleases also leads to a reduction of their ability to restrict the growth of λ.C. Experiments designed to estimate the time after adsorption at which restriction takes place indicate that phage DNA is probably restricted by a nuclease while passing through the periplasm.

Type
Short Papers
Copyright
Copyright © Cambridge University Press 1966

References

REFERENCES

Arber, W. & Dussoix, D. (1962). Host specificity of DNA produced by Escherichia coli. I. Host-controlled modification of bacteriophage. J. molec. Biol. 5 1836.CrossRefGoogle ScholarPubMed
Arber, W., Hattman, S. & Dussoix, D. (1963). On the host-controlled modification of bacteriophage λ. Virology, 21, 3035.CrossRefGoogle ScholarPubMed
Fukasawa, T. (1964). The course of infection with abnormal bacteriophage T4 containing non-glucosylated DNA on Escherichia coli strains. J. molec. Biol. 9, 525536.CrossRefGoogle ScholarPubMed
Molholt, B. & Fraser, D. (1965). Reversal of the restriction for host-modified T2 and T4 DNA upon conversion of non-permissive Escherichia coli to spheroplasts. Biochem. biophys. Res. Commun. 19, 571575.CrossRefGoogle ScholarPubMed
Schell, J. & Glover, S. W. (1966 a). The effect of heat on host-controlled restriction in Escherichia coli K (PI). J. gen. Microbiol. (in press).CrossRefGoogle Scholar
Schell, J. & Glover, S. W. (1966 b). On the localisation of a factor responsible for host-controlled restriction in Escherichia coli K(P1). Genet. Res. 7, 277279.CrossRefGoogle ScholarPubMed
Shortman, K. & Lehman, I. R. (1964). The deoxyribonucleases of Escherichia coli VI. Changes in enzyme levels in response to alterations in physiological state. J. biol. Chem. 239, 29642974.CrossRefGoogle ScholarPubMed