Hostname: page-component-586b7cd67f-rdxmf Total loading time: 0 Render date: 2024-11-23T00:47:53.587Z Has data issue: false hasContentIssue false
  • English
  • Français

Does Muller's ratchet work with selfing?

Published online by Cambridge University Press:  14 April 2009

R. Heller  and
J. Maynard Smith
R. Heller
Affiliation:
Arbeitsgruppe für Verhaltensforschung, Abteilung für Biologie, Ruhr-Universität Bochum, Postfach 10 21 48, 4630 Bochum 1, West Germany
J. Maynard Smith
Affiliation:
School of Biological Sciences, University of Sussex, Falmer, Brighton BN1 9QG
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The accumulation of deleterious mutations in a finite diploid selfing population is investigated. It is shown that the conditions for accumulation are very similar to those for the accumulation of mutations in an asexual population by ‘Muller's ratchet’. The ratchet is likely to operate in both types of population if there is a large class of slightly deleterious mutations.

Type
Research Article
Information
Genetics Research , Volume 32 , Issue 3 , November 1978 , pp. 289 - 293
Copyright
Copyright © Cambridge University Press 1978

References

REFERENCES

Allard, R. W., Kahler, A. L. & Clegg, M. T. (1977). Estimation of mating cycle components of selection in plants. In Measuring Selection in Natural Populations (ed. Christiansen, F. B. and Fenchel, T. M.), pp. 1–19. Berlin: Springer-Verlag.Google Scholar
Felsenstein, J. (1974). The evolutionary advantage of recombination. Genetics 78, 737–756.Google Scholar
Felsenstein, & Yokoyama, S. (1976). The evolutionary advantage of recombination. II. Individual selection for recombination. Genetics 83, 845–859.CrossRefGoogle ScholarPubMed
Haigh, J. (1978). The accumulation of deleterious genes in a population – Muller's ratchet. Theoretical Population Biology 14, 251–267.Google Scholar
Mukai, T., Chigusa, S. T., Mettler, L. E. & Crow, J. F. (1972). Mutation rate and dominance of genes affecting viability in Drosophila melanogaster. Genetics 72, 335–355.CrossRefGoogle ScholarPubMed
Muller, H. J. (1964). The relation of recombination to mutational advance. Mutation Research 1, 2–9.CrossRefGoogle Scholar