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The detection of a recessive visible gene in finite populations*

Published online by Cambridge University Press:  14 April 2009

Samuel Karlin  and
Simon Tavare
Samuel Karlin
Affiliation:
Department of Mathematics, Stanford University, Stanford, California 94305
Simon Tavare
Affiliation:
Department of Mathematics, Stanford University, Stanford, California 94305 Department of Mathematics, University of Utah, Salt Lake City, Utah 84112 (permanent address).
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Robertson, 1978, addressed the interesting problem of ascertaining the distribution of the time to detection of a recessive homozygote in a finite population. He was motivated in part by breeding and artificial selection practices. The same problem arises in the context of evolutionary processes and medical genetics since it refers to the time of first appearance as a homozygote of a new crossover event or a mutant gene.

Type
Research Article
Information
Genetics Research , Volume 37 , Issue 1 , February 1981 , pp. 33 - 46
Copyright
Copyright © Cambridge University Press 1981

References

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