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‘Dappled’ a new allele at the Mottled locus in the house mouse

Published online by Cambridge University Press:  14 April 2009

Rita J. S. Phillips
Rita J. S. Phillips
Affiliation:
Medical Research Council Radiobiological Research Unit, Harwell, Berkshire, England
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Dappled, a new completely sex-linked semi-dominant lethal mutation, is described. It is probably a new allele at the Mottled locus and has been given the symbol Modp.

Heterozygous adult females have a variegated coat very similar to that of Brindled and Mottled females; they have curly vibrissae at birth and some also have clubbed feet. All the characteristics are variable.

Hemizygous males die at about 17 days' gestation; they show a characteristic bending and thickening of the ribs and other skeletal defects. The cause of death is unknown.

Type
Research Article
Information
Genetics Research , Volume 2 , Issue 2 , July 1961 , pp. 290 - 295
Copyright
Copyright © Cambridge University Press 1961

References

REFERENCES

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