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Cytological location and lethal interactions of three Minute loci in chromosome 3 of Drosophila melanogaster

Published online by Cambridge University Press:  14 April 2009

Jaime Moscoso del Prado  and
Pedro Ripoll
Jaime Moscoso del Prado
Affiliation:
Centra de Biologia Molecular, CSIC, Universidad Autonoma de Madrid, Madrid-34, Spain
Pedro Ripoll
Affiliation:
Centra de Biologia Molecular, CSIC, Universidad Autonoma de Madrid, Madrid-34, Spain
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Summary

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Using seven newly induced duplications, three Minute loci have been located cytologically: M(3)hS 37 in 65F10–11; 66A (a new Minute locus), M(3)i in 67C, and M(3)hy in 68F; 69F. M(3)hS 37 and M(3)hy were previously thought to be allelic because they do not complement for lethality. The finding of Minute mutations with additive or synergistic rather than epistatic interactions makes us suspect that some other Minute mutations have been erroneously called allelic. The involvement of Minute loci in more than one biochemical pathway is discussed in view of the existence of synergistic interactions and of Minute loci without known mutant alleles.

Type
Research Article
Information
Genetics Research , Volume 42 , Issue 1 , August 1983 , pp. 59 - 63
Copyright
Copyright © Cambridge University Press 1983

References

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