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Caffeine-resistant mutants of Caenorhabditis elegans

Published online by Cambridge University Press:  14 April 2009

Philip S. Hartman
Philip S. Hartman
Affiliation:
Department of Biology, Texas Christian University, Fort Worth, TX 76129
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Summary

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Wild-type Caenorhabditis elegans fails to reach adulthood if L1 larvae are incubated in the presence of 30 mM or greater concentrations of caffeine. Eleven mutants have been isolated in which caffeine has a less pronounced effect on development. The mutations are recessive, define two genes, and have been mapped. The mechanism(s) of resistance is unknown.

Type
Research Article
Information
Genetics Research , Volume 49 , Issue 2 , April 1987 , pp. 105 - 110
Copyright
Copyright © Cambridge University Press 1987

References

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