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Aspects of temperature regulation in mice selected for large and small size

Published online by Cambridge University Press:  14 April 2009

Carol Becker Lynch  and
R. C. Roberts
Carol Becker Lynch
Affiliation:
Department of Biology, Wesleyan University, Middletown, Connecticut 06457
R. C. Roberts
Affiliation:
Institute of Animal Genetics, University of Edinburgh, West Mains Road, Edinburgh EH9 3JN
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We measured traits involved in physiological and behavioural thermoregulation in the 6 replicates of a selection experiment for large and small size (6-week weight) in mice, including control lines (18 lines in all). The observed genetic correlations between body size and thermoregulatory traits are consistent with a thermoregulatory advantage of large size, including decreased weight-specific food consumption and increased nest-building, with no change in body temperature. The differences in food consumption were closely paralleled by differences in amount of brown adipose tissue, strongly suggesting that much of the decreased efficiency of the small lines is due to heat production by brown fat. These results are consistent with available observations on natural populations, that selection for temperature adaptation probably has had some influence on body size in this species.

Type
Research Article
Information
Genetics Research , Volume 43 , Issue 3 , June 1984 , pp. 299 - 306
Copyright
Copyright © Cambridge University Press 1984

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