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Additive effects of the genes tabby and crinkled on tooth size in the mouse

Published online by Cambridge University Press:  14 April 2009

J. A. Sofaer
J. A. Sofaer
Affiliation:
University of Edinburgh, Department of Oral Medicine and Oral Pathology, Edinburgh EH1 1NR Department of Human Genetics, Western General Hospital, Edinburgh EH4 2XU

Summary

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The semi-dominant X-linked gene tabby (Ta) in the mouse and its recessive autosomal mimic crinkled (cr) produce the same mutant syndrome involving abnormalities of the hair, teeth and certain exocrine glands. Previous work has provided some indication of interaction between these loci in terms of vibrissa number. The results of the present study demonstrate that, for tooth size, mice doubly heterozygous for tabby and crinkled show a more extreme phenotype than either heterozygotes for tabby or crinkled alone.

Type
Research Article
Information
Genetics Research , Volume 33 , Issue 2 , April 1979 , pp. 169 - 174
Copyright
Copyright © Cambridge University Press 1979

References

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