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Absence of detectable gametic disequilibrium between the t-complex and linked allozyme-encoding loci in house mice

Published online by Cambridge University Press:  14 April 2009

Joseph H. Nadeau
Joseph H. Nadeau
Affiliation:
The Jackson Laboratory, Bar Harbor, ME 04609, U.S.A.
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To determine the extent of gametic disequilibrium between loci linked to the t-complex in house mice, alleles of four allozyme-encoding loci associated with eleven t-complexes recently found in wild mice and sixteen t-complexes maintained in laboratory colonies were identified. The allozyme-encoding loci included in the survey were complement component-3, kidney catalase, glyoxalase-1 and phosphoglycerate kinase-B. In contrast to published surveys showing strong disequilibrium between the H-2 complex, t-complex protein-1 and the t-complex, disequilibrium between the t-complex and linked allozyme-encoding loci was not detected. This result is discussed in terms of several hypotheses concerning the structure of mouse populations and the mechanisms maintaining gametic disequilibrium between the H-2 complex, t-complex protein-1 and the t-complex.

Type
Research Article
Information
Genetics Research , Volume 42 , Issue 3 , December 1983 , pp. 323 - 333
Copyright
Copyright © Cambridge University Press 1983

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