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Recent advances in the management of lung disease of prematurity

Part of: Bespoke shallow archive Weizmann

Published online by Cambridge University Press:  01 October 2001

Dawn L Darling  and
Neil N Finer
Dawn L Darling
Affiliation:
Division of Neonatology, Department of Pediatrics, Universiity of California, San Diego, California
Neil N Finer
Affiliation:
Division of Neonatology, Department of Pediatrics, Universiity of California, San Diego, California
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Abstract

Despite many advances in the management of lung disorders of premature infants, respiratory distress syndrome (RDS) remains the major cause of morbidity and mortality in the preterm infant. Approximately 30% of infants born at less than 34 weeks gestation will develop RDS, secondary to deficiency in surfactant production by alveolar type II pneumocytes. Without surfactant, work of breathing is increased and gas exchange impaired by diffuse atelectasis, reduced pulmonary compliance and ventilation perfusion mismatch.

Type
Research Article
Information
Fetal and Maternal Medicine Review , Volume 12 , Issue 4 , November 2001 , pp. 229 - 248
Copyright
© 2001 Cambridge University Press

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