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MARFAN SYNDROME AND PREGNANCY: CLINICAL IMPLICATIONS AND MANAGEMENT

Part of: Bespoke shallow archive Weizmann

Published online by Cambridge University Press:  04 August 2010

ARIADNA C GRIGORIU ,
JACK COLMAN ,
CANDICE K SILVERSIDES ,
RACHEL WALD ,
SAMUEL C SIU  and
MATHEW SERMER
ARIADNA C GRIGORIU
Affiliation:
Department of Obstetrics and Gynaecology, Mount Sinai Hospital, University of Toronto.
JACK COLMAN
Affiliation:
Department of Medicine, Mount Sinai Hospital, University of Toronto.
CANDICE K SILVERSIDES
Affiliation:
Department of Medicine, University Health Network, University of Toronto.
RACHEL WALD
Affiliation:
Department of Medicine, University Health Network, University of Toronto.
SAMUEL C SIU
Affiliation:
Department of Cardiology, Schulich School of Medicine and Dentistry, University of Western Ontario.
MATHEW SERMER*
Affiliation:
Department of Obstetrics and Gynaecology, Mount Sinai Hospital, University of Toronto.
*
Mathew Sermer, Mount Sinai Hospital, 600 University Avenue, Room 1007, Toronto, Ontario M5G 1×5, email address: [email protected]
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Extract

Marfan syndrome (MFS) is an autosomal dominant connective tissue disorder that affects multiple organ systems, primarily the cardiovascular, ocular and skeletal. It is the most common inherited condition affecting the heart and the aorta, occurring in 1:5000–1:9800 people. There is no ethnic or gender predisposition; 20 to 35% of cases arise from de novo mutations.

Type
Research Article
Information
Fetal and Maternal Medicine Review , Volume 21 , Issue 3 , August 2010 , pp. 225 - 241
Copyright
Copyright © Cambridge University Press 2010

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References

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