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FETOSCOPIC SURGERY FOR IN-UTERO MANAGEMENT OF CONGENITAL DIAPHRAGMATIC HERNIA

Published online by Cambridge University Press:  11 April 2006

SCOTT M NELSON
Affiliation:
Reproductive and Maternal Medicine, Division of Developmental Medicine, University of Glasgow, UK
ALAN D CAMERON
Affiliation:
Department of Obstetrics and Fetal Medicine, Queen Mother's Hospital, Glasgow, UK
JAN A DEPREST
Affiliation:
Department of Gynaecology and Obstetrics, Fetal Medicine Unit, University Hospital Gasthuisberg, Leuven, Belgium

Abstract

Until recently two possibilities were available to the expectant parents of a fetus diagnosed with a congenital diaphragmatic hernia: termination of pregnancy or continuation of the pregnancy until term with a potential change in the place of delivery. Open fetal surgery has been used to treat a growing number of congenital malformations with life-threatening or highly morbid consequences including congenital diaphragmatic hernia. However, its effectiveness is limited by the occurrence of preterm labour, chorioamniotic membrane separation, preterm prelabour rupture of the membranes and altered fetal homeostasis. These problems were the impetus for the development of minimal access fetal surgery. Developments in endoscopic surgical technology over the past three decades have provided the opportunity to develop techniques adapted for prenatal fetal intervention.

Type
Research Article
Copyright
2006 Cambridge University Press

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