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FEATURES OF THE CONGENITAL CMV INFECTION IN THE UNBORN AND NEWBORN INFANT

Part of: Bespoke shallow archive Weizmann

Published online by Cambridge University Press:  01 August 2007

G BENOIST  and
Y VILLE
G BENOIST*
Affiliation:
Y. Ville, Service de Gynecolgie Obstetrique, Centre Hospitalier Intercommunal de Poissy-St Germain, Poissy, France 10 rue du Champ Gaillard, 78300 Poissy, France
Y VILLE
Affiliation:
Y. Ville, Service de Gynecolgie Obstetrique, Centre Hospitalier Intercommunal de Poissy-St Germain, Poissy, France 10 rue du Champ Gaillard, 78300 Poissy, France
*
Service de Gynecolgie Obstetrique, Centre Hospitalier Intercommunal de Poissy-St Germain, 10 rue du Champ Gaillard, 78300 Poissy, France
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Extract

Cytomegalovirus (CMV) is the most frequent cause of congenital viral infection,1 with a prevalence of 0.5 to 1% of all live births, and the leading infectious cause of sensorineural deafness and mental retardation.1 As other Herpesviridae, CMV fetal infection can develop following both primary and recurrent maternal infection. Vertical transmission rate is around 30% following primary infection and 2 to 3% following recurrent infection.2 Effects on the unborn as well as on the newborn are widely variable. It is estimated that only 5 to 10% of infected newborns have symptoms at birth, whereas around 90% of congenitally infected infants are asymptomatic although 5–15% of these infants will develop some degree of sensorineural hearing loss.3

Type
Research Article
Information
Fetal and Maternal Medicine Review , Volume 18 , Issue 3 , August 2007 , pp. 181 - 199
Copyright
Copyright © Cambridge University Press 2007

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