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Doppler ultrasonography in uteroplacental insufficiency

Published online by Cambridge University Press:  10 October 2008

Domenico Arduini  and
Giuseppe Rizzo
Domenico Arduini*
Affiliation:
Department of Obstetrics and Gynecology, Universities of Ancona and “Tor Vergata”Rome, Italy.
Giuseppe Rizzo
Affiliation:
Department of Obstetrics and Gynecology, Universities of Ancona and “Tor Vergata”Rome, Italy.
*
Prof Domenico Arduini, Cattedra di Medicina dell';etá prenatale, Clinica ostetrica a ginecologica, Universitá di Ancona, Via Corridoni, 11, 60123 Ancona, Italy
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Extract

Much of our understanding of uteroplacental insufficiency has been derived from animal research and the study of the pathology of human placental and uterine biopsies. These studies have shown how the placenta plays a major role in the development of normal pregnancy and how placental dysfunction is generally caused by factors interfering with the normal growth of the uteroplacental and/or fetoplacental circulations. These abnormalities lead to a deficient supply of oxygen and nutrients to the fetus and to several complications of pregnancy such as gestational hypertension, preeclampsia and intrauterine growth retardation (IUGR).

Type
Articles
Information
Fetal and Maternal Medicine Review , Volume 6 , Issue 3 , August 1994 , pp. 153 - 166
Copyright
Copyright © Cambridge University Press 1994

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References

1Benirschke, K, Kauffmann, P. Pathology of the human placenta. New York: Springer Verlag, 1990.CrossRefGoogle Scholar
2Lin, CC, Evans, MI. Intrauterine growth retardation. Pathophysiology and clinical management. New York: McGraw-Hill, 1984.Google Scholar
3Blechner, JN, Stenger, VG, Prystowsky, H. Uterine blood flow in women at term. Am J Obstet Gynecol 1974; 120: 633–38.CrossRefGoogle ScholarPubMed
4Creasy, RK, Barret, CT, de Swiet, M, Kahanpaa, KV, Rudolph, AM. Experimental growth retardation in the sheep. Am J Obstet Gynecol 1972; 112: 566–73.CrossRefGoogle ScholarPubMed
5Gu, W, Jones, CT, Parer, JT. Metabolic and cardiovascular effects on fetal sheep of sustained reduction of uterine blood flow. J Physiol 1985; 368: 109–21.CrossRefGoogle ScholarPubMed
6Brosens, I, Robertson, WB, Dixon, HG. The physiological response of the vessels of the placental bed to normal pregnancy. J Pathol Bacteriol 1967; 93: 569–79.CrossRefGoogle ScholarPubMed
7Sheppard, BL, Bonnar, J. An ultrastructural study of uteroplacental spiral arteries in hypertensive and normotensive pregnancy and fetal growth retardation. Br J Obstet Gynaecol 1981; 88: 695–705.CrossRefGoogle ScholarPubMed
8Giles, WB, Trudinger, BJ, Baird, PJ, Cook, CM. Fetal umbilical artery flow velocity waveforms and placental resistance: pathological correlation. Br J Obstet Gynaecol 1985; 92: 31–36.CrossRefGoogle ScholarPubMed
9Bracero, LA, Beneck, D, Kirshenbaum, N, Peiffer, M, Stalter, P, Schulman, H. Doppler velocimetry and placental disease. Am J Obstet Gynecol 1989; 161: 388–93.CrossRefGoogle ScholarPubMed
10Soothill, PW, Nicolaides, KH, Campbell, S. Prenatal asphyxia, hyperlactaemia and erythroblastosis in growth retarded fetuses. Br Med J 1987; 294: 1051–53.CrossRefGoogle Scholar
11Economides, DL, Nicolaides, KH. Blood glucose and oxygen tension in small for gestational age fetuses. Am J Obstet Gynecol 1989; 160: 385–89.CrossRefGoogle ScholarPubMed
12Cetin, I, Corbetta, C, Sereni, LP, Marconi, AM, Bozzetti, P, Pardi, G. Umbilical amino acid concentrations in normal and growth retarded fetuses sampled in utero by cordocentesis. Am J Obstet Gynecol 1990; 162: 253–61.CrossRefGoogle ScholarPubMed
13Rudolph, AM. Distribution and regulation of blood flow in the fetal and neonatal lamb. Circ Res 1985; 57: 811–21.CrossRefGoogle ScholarPubMed
14Peeters, LLH, Sheldon, RF, Jones, MD, Makowsky, EI, Meschia, G. Blood flow to fetal organ as a function of arterial oxygen content. Am J Obstet Gynecol 1979; 135: 637–46.CrossRefGoogle ScholarPubMed
15Creasy, RK, de Swiet, M, Kahanpaa, KV, Young, WP, Rudolph, AM. Pathophysiological changes in the foetal lamb with growth retardation. In: Comline, RS, Croos, KW, Dawes, GS, Nathanielz, PW eds, Foetal and neonatal physiology. London: Cambridge University Press, 1973: 398–402.Google Scholar
16Visser, GHA, Bekedam, DJ. Serial observations on adaptation in the human fetus. In: Dawes, GS, Borruto, F, Zacutti, A, Zacutti, A Jr. eds, Fetal autonomy and adaptation. Chichester: Wiley, 1990: 67–80.Google Scholar
17Arduini, D, Rizzo, G, Boccolini, MR, Romanini, C, Mancuso, S. Functional assessment of uteroplacental and fetal circulations by means of color Doppler ultrasonography. J Ultrasound Med 1990; 9: 249–53.CrossRefGoogle ScholarPubMed
18Alfirevic, Z, Kurjak, A. Transvaginal colour Doppler ultrasound in normal and abnormal early pregnancy. J Perinat Med 1990; 18: 173–80.CrossRefGoogle ScholarPubMed
19Arduini, D, Rizzo, G, Romanini, C. Doppler ultrasonography in early pregnancy does not predict adverse pregnancy outcome. Ultrasound Obstet Gynecol 1991; 1: 180–85.CrossRefGoogle Scholar
20Thaler, I, Manor, D, Itskovitz, J, Rottem, S, Levit, N, Timor, Trish I et al. Changes in uterine blood flow during human pregnancy. Am J Obstet Gynecol 1990; 162: 121–25.CrossRefGoogle ScholarPubMed
21Schulman, H, Fleisher, A, Farmakides, G, Bracero, L, Rochelson, B, Grunfeld, L. Development of uterine artery compliance in pregnancy as detected by ultra-sound. Am J Obstet Gynecol 1986; 155: 1031–36.CrossRefGoogle Scholar
22Trudinger, BJ, Giles, WB, Cook, CM. Utero-placental blood flow velocity time waveforms in normal and complicated pregnancies. Br J Obstet Gynaecol 1985; 92: 39–45.CrossRefGoogle Scholar
23Campbell, S, Pearce, JMF, Hackett, G, Cohen-Overbeek, TE, Hernandez, C. Qualitative assessment of uteroplacental blood flow: early screening test for high-risk pregnancies. Obstet Gynecol 1986; 68: 649–53.Google ScholarPubMed
24Arduini, D, Rizzo, G, Romanini, C, Mancuso, S. Utero-placental blood flow velocity waveforms as predictors of pregnancy-induced hypertension. Eur J Obstet Gynecol Reprod Biol 1987; 26: 335–41.CrossRefGoogle ScholarPubMed
25Arduini, D, Rizzo, G. Normal values of Pulsatility Index from fetal vessels: a cross sectional study on 1556 healthy fetuses. J Perinat Med 1990; 18: 165–72.CrossRefGoogle ScholarPubMed
26Arduini, D, Rizzo, G. Umbilical artery velocity wave-forms in early pregnancy: a transvaginal color Doppler study. J Clin Ultrasound 1991; 19: 335–39.CrossRefGoogle Scholar
27Rochelson, B, Schulman, H, Farmakides, J, Bracero, L, Ducey, J, Fleisher, A et al. The significance of absent end diastolic velocity in umbilical artery velocity waveforms. Am J Obstet Gynecol 1987; 156: 1213–17.CrossRefGoogle ScholarPubMed
28Hackett, GA, Campbell, S, Gamsu, H, Cohen-Overbeek, T, Pearce, JMF. Doppler studies in the growth retarded fetus and prediction of neonatal necrotising enterocolitis, haemorrhage and neonatal morbidity. Br Med J 1987; 294: 13–18.CrossRefGoogle ScholarPubMed
29Vyas, S, Nicolaides, KH, Campbell, S. Renal flow-velocity waveforms in normal and hypoxemic fetuses. Am J Obstet Gynecol 1989; 161: 168–72.CrossRefGoogle ScholarPubMed
30Arduini, D, Rizzo, G. Fetal renal artery velocity wave-forms and amniotic fluid volume in growth-retarded and post-term fetuses. Obstet Gynecol 1991; 77: 370–74.Google Scholar
31Kurjak, A, Predanic, M, Kupesic-Urek, S, Funduk-Kujak, B, Demarin, V, Salihagic, A. Transvaginal color Doppler study of middle cerebral artery blood flow in early normal and abnormal pregnancy. Ultrasound Obstet Gynecol 1992; 2: 424–28.CrossRefGoogle ScholarPubMed
32Mari, G, Moise, KJ, Deter, RL, Kirshon, B, Carpenter, RJ, Hutha, JC. Doppler assessment of the pulsatility index in the cerebral circulation of the human fetus. Am J Obstet Gynecol 1989; 160: 698–703.CrossRefGoogle ScholarPubMed
33Bilardo, CM, Nicolaides, KH, Campbell, S. Doppler measurement of fetal and uteroplacental circulation: relationship with umbilical venous blood gases measured at cordocentesis. Am J Obstet Gynecol 1990; 162: 115–21.CrossRefGoogle Scholar
34Arduini, D, Rizzo, G, Romanini, C, Mancuso, S. Are blood flow velocity waveforms related to umbilcal cord acid-base status in the human fetus? Gynecol Obstet Invest 1989; 27: 183–87.CrossRefGoogle Scholar
35Rizzo, G, Luciano, R, Arduini, D, Rizzo, C, Tortorolo, G, Romanini, C et al. Prenatal cerebral Doppler ultra-sonography and neonatal neurological outcome. J Ultrasound Med 1989; 8: 237–40.CrossRefGoogle Scholar
36Rizzo, G, Arduini, D, Romanini, C, Mancuso, S. Doppler echocardiographic assessment of atrioventricular velocity waveforms in normal and small for gestational age fetuses. Br J Obstet Gynaecol 1988; 95: 65–69.CrossRefGoogle ScholarPubMed
37Reed, KL, Anderson, CF, Shenker, L. Changes in intracardiac Doppler blood flow velocities in fetuses with absent umbilical artery diastolic flow. Am J Obstet Gynecol 1987; 157: 774–79.CrossRefGoogle ScholarPubMed
38Groenenberg, IAL, Wladimiroff, JW, Hop, WCJ. Fetal cardiac and peripheral arterial flow velocity waveforms in intrauterine growth retardation. Circulation 1989; 80: 1711–17.CrossRefGoogle ScholarPubMed
39Rizzo, G, Arduini, D. Fetal cardiac function in intrauterine growth retardation. Am J Obstet Gynecol 1991; 165: 876–82.CrossRefGoogle ScholarPubMed
40Rizzo, G, Arduini, D, Romanini, C, Mancuso, S. Doppler echocardiographic evaluation of time to peak velocity in the aorta and pulmonary artery of small for gestational age fetuses. Br J Obstet Gynaecol 1990; 97: 603–607.CrossRefGoogle Scholar
41Al-Ghazali, W, Chita, SK, Chapman, MG, Allan, LD. Evidence of redistribution of cardiac output in asymmetrical growth retardation. Br J Obstet Gynaecol 1989; 96: 697–704.CrossRefGoogle ScholarPubMed
42Rizzo, G, Arduini, D, Romanini, C. Inferior vena cava flow velocity waveforms in appropriate and small for gestational age fetuses. Am J Obstet Gynecol 1992; 166: 1271–80.CrossRefGoogle ScholarPubMed
43Rizzo, G, Capponi, A, Romanini, C. Ductus venosus velocity waveforms in appropriate and small for gestational age fetuses. Early Hum Dev 1994; 38: in press.Google Scholar
44Rizzo, G, Arduini, D, Romanini, C. Pulsations in umbilical vein: a physiological finding in early pregnancy. Am J Obstet Gynecol 1992; 167: 675–77.CrossRefGoogle Scholar
45Indick, JH, Chen, V, Reed, KL. Association of umbilical venous with inferior vena cava blood flow velocities. Obstet Gynecol 1991; 77: 551–57.Google Scholar
46McParland, P, Pearce, JM, Chamberlain, GVP. Doppler ultrasound and aspirin in recognition and prevention of pregnancy-induced hypertension. Lancet 1989; 335: 1552–55.CrossRefGoogle Scholar
47Harrington, KF, Campbell, S, Bewley, S, Bower, S. Doppler velocimetry studies of the uterine arteries in the early prediction of pre-eclampsia and intrauterine growth retardation. Eur J Obstet Gynecol Reprod Med 1991; 42: S14–S20.Google Scholar
48Chambers, SE, Hoskins, RS, Haddad, NG, Johnstone, FD, McDicken, WN, Muir, BB. A comparison of fetal abdominal circumference measurements and Doppler ultrasound in the prediction of small for dates babies and growth retarded pregnancies. Br J Obstet Gynaecol 1989; 96: 803–808.CrossRefGoogle Scholar
49Jacobson, SL, Imhof, R, Manning, V, Little, D, Rey, E et al. The value of Doppler assessment of the uteroplacental circulation in predicting preeclampsia and intrauterine growth retardation. Am J Obstet Gynecol 1990; 162: 110–14.CrossRefGoogle ScholarPubMed
50Newnham, JP, Patterson, LL, James, RJ, Diepeveen, DA, Reid, SE. An evaluation of the efficacy of Doppler flow velocity waveforms analysis as a screening test in pregnancy. AM J Obstet Gynecol 1990; 162: 403–10.CrossRefGoogle ScholarPubMed
51Fleisher, A, Schulman, H, Farmakides, G, Bracero, L, Blatnner, P, Randolph, G. Umbilical artery velocity waveforms and intrauterine growth retardation. Am J Obstet Gynecol 1985; 151: 502–505.CrossRefGoogle Scholar
52Giles, WB, Lingman, G, Marsal, K, Trudinger, BJ. Fetal volume blood flow and umbilical artery velocity waveforms analysis: a comparison. Br J Obstet Gynaecol 1986; 93: 461–65.CrossRefGoogle ScholarPubMed
53Arduini, D, Rizzo, G, Romanini, C, Mancuso, S. Fetal blood flow velocity waveforms as predictors of growth retardation. Obstet Gynecol 1987; 70: 7–10.Google ScholarPubMed
54Divon, MY, Guidetti, DA, Braverman, JJ, Oberlander, E, Langer, O, Merkatz, IR. Intrauterine growth retardation - a prospective study of the diagnostic value of real time sonography combined with umbilical artery flow velocimetry. Obstet Gynecol 1988; 72: 611–14.Google ScholarPubMed
55Dempster, J, Mires, GJ, Patel, N, Taylor, DJ. Umbilical artery velocity waveforms: poor association with small for gestational age fetuses. Br J Obstet Gynaecol 1989; 96: 692–96.CrossRefGoogle Scholar
56Beattle, RB, Dornan, JC. Antenatal screening for intrauterine growth retardation with umbilical artery velocimetry. Br Med J 1989; 298: 631–35.CrossRefGoogle Scholar
57Sijmons, EA, Reuwer, PJ, van Beek, E, Bruinse, HW. The validity of screening for small for gestational age and low weight for length infants by Doppler ultrasound. Br J Obstet Gynaecol 1989; 96: 557–61.CrossRefGoogle ScholarPubMed
58Arduini, D, Rizzo, G. Prediction of fetal outcome in small for gestational age fetuses. Comparison of Doppler measurements obtained from different fetal vessels. J Perinat Med 1992; 20: 29–38.CrossRefGoogle ScholarPubMed
59Bekedam, DJ, Visser, GHA, van der Zee, AGJ, Snijders, R, Poelmann-Weesjes, G. Abnormal velocity wave-forms of the umbilical artery in growth retarded fetuses: relationship to antepartum late heart rate decelerations and outcome. Early Hum Dev 1990; 24: 79–89.CrossRefGoogle Scholar
60Arduini, D, Rizzo, G, Romanini, C. The development of abnormal heart rate patterns after absent end diastolic velocity in umbilical artery: analysis of risk factors. Am J Obstet Gynecol 1993; 168: 43–49.CrossRefGoogle ScholarPubMed
61Soothill, PW, Ajayi, RA, Campbell, S, Ross, EM, Candy, DCA, Snijders, RM et al. Relationship between acidemia at cordocentesis and subsequent neurodevelopment. Ultrasound Obstet Gynecol 1992; 2: 80–84.CrossRefGoogle ScholarPubMed
62Todds, AL, Trudinger, BJ, Cole, MJ, Cooney, GH. Antenatal tests of fetal welfare and development at age 2 years. Am J Obstet Gynecol 1992; 167: 66–71.CrossRefGoogle Scholar
63Visser, GHA, Stitger, RH, Bruinse, HW. Management of the growth-retarded fetus. Eur J Obstet Gynecol Repr Biol 1991; 42: S73–S78.Google ScholarPubMed
64Arduini, D, Rizzo, G, Romanini, C. Changes of pulsatility index from fetal vessels preceding the onset of late decelerations in growth retarded fetuses. Obstet Gynecol 1992; 79: 605–10.Google ScholarPubMed
65Mari, G, Wasserstrum, N. Flow velocity waveforms of the fetal circulation preceding fetal death in a case of lupus anticoagulant. AM J Obstet Gynecol 1991; 164: 776–78.CrossRefGoogle Scholar
66Rizzo, G, Capponi, A, Pietropolli, A, Cacciatore, C, Arduini, D, Romanini, C. Cardiac and extra-cardiac flow changes preceding intrauterine fetal death. Ultra-sound Obstet Gynecol 1994; 4: 139–42.CrossRefGoogle Scholar
67Richardson, BS, Rurak, D, Patrick, JE, Homan, J, Carmichael, L. Cerebral oxidative metabolism during sustained hypoxaemia in fetal sheep. J Dev Physiol 1989; 11: 37–43.Google ScholarPubMed