Hostname: page-component-78c5997874-lj6df Total loading time: 0 Render date: 2024-11-20T03:23:13.949Z Has data issue: false hasContentIssue false
  • English
  • Français

Asthma in pregnancy

Published online by Cambridge University Press:  10 October 2008

Catherine Nelson-Piercy  and
Michael de Swiet
Catherine Nelson-Piercy*
Affiliation:
Queen Charlotte's and Chelsea Hospital, London, UK
Michael de Swiet
Affiliation:
Queen Charlotte's and Chelsea Hospital, London, UK
*
Dr Catherine Nelson-Piercy, Department of Obstetric Medicine, Queen Charlotte’s and Chelsea Hospital, Goldhawk Road, London W6 0XG, UK
Get access Rights & Permissions [Opens in a new window]

Extract

Asthma is the most common significant chronic medical condition affecting young adults and it is therefore often encountered in pregnancy. Approximately 3% of women of child-bearing age suffer some degree of asthma and this prevalence is increasing. Some of the apparent increase is due to heightened awareness of the condition, although air pollution and increased childhood exposure to house dust mite may also be contributing.

Type
Articles
Information
Fetal and Maternal Medicine Review , Volume 6 , Issue 4 , November 1994 , pp. 181 - 189
Copyright
Copyright © Cambridge University Press 1994

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1Littlejohn, PI, Ebrahim, S, Anderson, R. Prevalence and diagnosis of chronic respiratory symptoms in adults. Br Med J 1989; 298: 1556–60.CrossRefGoogle Scholar
2Burnley, PG, Chin, S, Rowa, RJ. Has the prevalence of asthma increased in children? Evidence from the national study of health and growth. Br Med J 1990; 300: 1306–10.CrossRefGoogle Scholar
3Sporik, R, Holgate, ST, Platts-Mills, TAE, Cogswell, JJ. Exposure to house-dust mite allergen Der p 1 and the development of asthma in childhood. A prospective study. N Engl J Med 1990; 323: 502–507.CrossRefGoogle Scholar
4De Swiet, M. Disease of the respiratory system. In: De Swiet ed, Medical disorders in obstetric practice. Oxford: Blackwell, 1989; 1–47.Google Scholar
5Turner-Warwick, M. Epidemiology of nocturnal asthma. Am J Med 1988; 85: 6–8.CrossRefGoogle ScholarPubMed
6Sims, CD, Chamberlain, GVP, de Swiet, M. Lung function tests in bronchial asthma during and after pregnancy. Br J Obstet Gynaecol 1976; 83: 434–37.CrossRefGoogle Scholar
7De Swiet, M. Respiratory disease in pregnancy. Postgrad Med J 1979; 55: 325–28.CrossRefGoogle ScholarPubMed
8Gluck, JC, Gluck, P. The effects of pregnancy on asthma: a prospective study. Ann Allergy 1976; 37: 164–68.Google ScholarPubMed
9White, RJ, Coutts, I, Gibbs, CJ, MacIntyre, C. A prospective study of asthma during pregnancy and the puerperium. Respir Med 1989; 83: 103–106.CrossRefGoogle ScholarPubMed
10Juniper, EF, Daniel, EE, Roberts, RS, Kline, PA, Hargreave, FE, Newhouse, MT. Improvement in airway responsiveness and asthma severity during pregnancy. A prospective study. Am Rev Resp Dis 1989; 140: 924–31.CrossRefGoogle ScholarPubMed
11Nolten, WE, Rueckert, PA. Elevated free cortisol index in pregnancy: possible regulating mechanisms. Am J Obstet Gynecol 1981; 139: 492–98.CrossRefGoogle Scholar
12Gordon, M, Niswander, KR, Berendes, H, Kantor, AG. Fetal morbidity following potentially anoxigenic obstetric conditions. VII. Bronchial asthma. Am J Obstet Gynecol 1970; 106: 421–29.CrossRefGoogle ScholarPubMed
13Bahna, SL, Bjerkedal, T. The course and outcome of pregnancy in women with bronchial asthma. Acta Allergologica 1972; 27: 397–400.CrossRefGoogle ScholarPubMed
14Schatz, M, Patterson, R, Zeitz, S, O’Rourke, J, Melam, H. Corticosteroid therapy for the pregnant asthmatic patient. JAMA 1975; 233: 804–807.CrossRefGoogle ScholarPubMed
15Greenberger, PA, Patterson, R. The outcome of pregnancy complicated by severe asthma. Allergy Proc 1988; 9: 539–43.CrossRefGoogle ScholarPubMed
16Schatz, M, Zeiger, RS, Hoffman, CP. Intrauterine growth is related to gestational pulmonary function in pregnant asthmatic women. Kaiser-Permanente asthma and pregnancy study group. Chest 1990; 98: 389–92.CrossRefGoogle ScholarPubMed
17Apter, AJ, Greenberger, PA, Patterson, R. Outcomes of pregnancy in adolescents with severe asthma. Arch Intern Med 1989; 149: 2571–75.CrossRefGoogle ScholarPubMed
18Fitzsimons, R, Greenberger, PA, Patterson, R. Outcome of pregnancy in women requiring corticosteroids for severe asthma. J Allergy Clin Immunol 1986; 78: 349–53.CrossRefGoogle ScholarPubMed
19Doucette, JT, Bracken, MB. Possible role of asthma in the risk of preterm labor and delivery. Epidemiology 1993; 4: 143–50.CrossRefGoogle ScholarPubMed
20Perlow, JH, Montgomery, D, Morgan, MA, Towers, CV, Porto, M. Severity of asthma and perinatal outcome. Am J Obstet Gynecol 1992; 167: 963–67.CrossRefGoogle ScholarPubMed
21Lehrer, S, Stone, J, Lapinski, R, Lockwood, CJ, Schachter, BS, Berkowitz, R et al. Association between pregnancy-induced hypertension and asthma during pregnancy. Am J Obstet Gynecol 1993; 168: 1463–66.CrossRefGoogle ScholarPubMed
22Steenius-Aarniala, B, Piirila, P, Teramo, K. Asthma and pregnancy: a prospective study of 198 pregnancies. Thorax 1988; 43: 12–18.CrossRefGoogle Scholar
23 CLASP (Collaborative low-dose aspirin study in pregnancy) Collaborative Group. CLASP: a randomised trial of low-dose aspirin for the prevention and treatment of pre-eclampsia among 9364 pregnant women. Lancet 1994; 343: 616–29.Google Scholar
24Schatz, M, Zeiger, RS, Hoffman, CP, Saunders, BS, Harden, KM, Forsythe, AB. Increased transient tachypnea of the newborn in infants of asthmatic mothers. Am J Dis Child 1991; 145: 156–58.Google ScholarPubMed
25Patterson, CA, Graves, WL, Bugg, G, Sasso, SC, Brann, AW. Antenatal and intrapartum factors associated with the occurence of seizures in term infant. Obstet Gynecol 1989; 74: 361–65.Google Scholar
26Schreier, L, Cutler, RM, Saigal, V. Respiratory failure in asthma during the third trimester. Am J Obstet Gynecol 1989; 160: 80–81.CrossRefGoogle ScholarPubMed
27Gilchrist, DM, Fieldman, JM, Werker, D. Life-threatening status asthmaticus at 12.5 weeks gestation. Report of a normal pregnancy outcome. Chest 1991; 100: 285–86.CrossRefGoogle ScholarPubMed
28Gruteke, P, Askari, A, Chatterjee, TK, Chopra, MP, Nwokolo, FF. Artificial ventilatory management in a severe, pregnant asthmatic - a case report. Br J Clin Pract 1992; 46: 63–64.CrossRefGoogle Scholar
29Lao, TT, Huengsburg, B. Labour and delivery in mothers with asthma. Eur J Obstet Gynecol Reprod Biol 1990; 35: 183–90.CrossRefGoogle ScholarPubMed
30Moore-Gillon, JC. Pregnancy and the asthmatic. Respir Med 1991; 85: 451–52.CrossRefGoogle ScholarPubMed
31Moore-Gillon, JC. Asthma in pregnancy. Contemp Rev Obstet Gynaecol 1993; 5: 25–29.Google Scholar
32 British Thoracic Society. Guidelines for the management of asthma: a summary. Br Med J 1993; 306: 776–82.CrossRefGoogle Scholar
33Beasley, R, Cushley, M, Holgate, ST. A self-management plan in the treatment of adult asthma. Thorax 1989; 44: 200–204.CrossRefGoogle ScholarPubMed
34Charlton, I, Charlton, G, Broomfield, J, Mullee, MA. Evaluation of peakflow and symptom only self management plans for control of asthma in general practice. Br Med J 1990; 301: 1355–59.CrossRefGoogle Scholar
35Morgan, DJ. Clinical pharmacokinetics of beta-agonists. Clin Pharmacokinet 1990; 18: 270–94.CrossRefGoogle ScholarPubMed
36Slotkin, TA, Baker, FE, Dobbins, SS, Eylers, JP, Lappi, SE, Seidler, FJ. Prenatal terbutaline exposure in the rat: selective effects on development of noradrenergic projections to cerebellum. Brain Res Bull 1989; 23: 263–65.CrossRefGoogle ScholarPubMed
37Slotkin, TA, Kudlacz, EM, Lappi, SE, Tayyeb, MI, Seidler, FJ. Fetal terbutaline exposure causes selective postnatal increases in cerebellar alpha-adrenergic receptor binding. Life Sci 1990; 47: 2051–57.CrossRefGoogle ScholarPubMed
38Schatz, M, Zeiger, RS, Harden, KM et al. The safety of inhaled β-agonist bronchodilators during pregnancy. J Allergy Clin Immunol 1988; 82: 686–95.CrossRefGoogle ScholarPubMed
39Wilson, J. Utilisation du cromoglycate de sodium au cours de la grossesse. Acta Ther 1982; 8: 45–51.Google Scholar
40British National Formulary. British Medical Association and Royal Pharmaceutical Society of Great Britain 1993; 26: 104.Google Scholar
41Labovitz, E, Spector, S. Placental theophylline transfer in pregnant asthmatics. JAMA 1982; 247: 786–88.CrossRefGoogle ScholarPubMed
42Greenberger, P, Patterson, R. Safety of therapy for allergic symptoms during pregnancy. Ann Intern Med 1978; 89: 234–37.CrossRefGoogle ScholarPubMed
43Heinonen, DP, Stone, D, Shapiro, S. Birth defects and drugs in pregnancy. Littleton, Mass: Publishing Sciences Group, 1977.Google Scholar
44Carter, BL, Driscoll, CF, Smith, GD. Theophylline clearance during pregnancy. Obstet Gynecol 1986; 88: 146–49.Google Scholar
45Frederiksen, MC, Ruo, TI, Chow, MJ, Atkinson, AJ Jr. Theophylline pharmacokinetics in pregnancy. Clin Pharmacol Ther 1986; 40: 321–28.CrossRefGoogle ScholarPubMed
46Gardner, MJ, Schatz, M, Cousins, L et al. Longitudinal effects of pregnancy on the pharmacokinetics of theophylline. Eur J Clin Pharmacol 1987; 31: 289–95.CrossRefGoogle Scholar
47Park, JM, Schmer, V, Myers, TL. Cardiovascular anomalies associated with prenatal exposure to theophylline. South Med J 1990; 83: 1487–88.CrossRefGoogle ScholarPubMed
48Nagahama, H, Nagano, K, Yamanaka, L, Kasagawa, J, Seki, I, Suzuki, Y. Severe theophylline toxicity in a pregnant asthmatic patient. Masui 1993; 42: 1076–80.Google Scholar
49Harris, DM. Some properties of beclomethasone dipropionate and related steroids in man. Postgrad Med J 1975; 51: 20–25.Google ScholarPubMed
50Greenberger, P, Patterson, R. Beclomethasone dipropionate for severe asthma during pregnancy. Ann Intern Med 1983; 98: 478–80.CrossRefGoogle ScholarPubMed
51Marion-Brown, H, Storey, G. Beclomethasone dipropionate aerosol in long-term treatment of perennial and seasonal asthma in children and adults. A report of five and a half years experience in 600 asthmatic patients. Br J Pharmacol 1977; 4: 529s–67s.Google Scholar
52Fainstat, T. Cortisone-induced congenital cleft palate in rabbits. Endocrinology 1954; 55: 502.CrossRefGoogle ScholarPubMed
53Snyder, RD, Snyder, D. Corticosteroids for asthma during pregnancy. Ann Allergy 1978; 41: 340–41.Google ScholarPubMed
54Arad, I, Landau, H. Adrenocortical reserve of neonates born of long-term, steroid-treated mothers. Eur J Pediatr 1984; 142: 279–80.CrossRefGoogle ScholarPubMed
55Fitzpatrick, MF, Mackay, T, Driver, H, Douglas, NJ. Salmeterol in nocturnal asthma: a double blind, placebo-controlled trial of a long acting inhaled β2-agonist. Br Med J 1990; 301: 1365–68.CrossRefGoogle Scholar
56Metzger, WJ. Indications for allergen immunotherapy during pregnancy. Compr Ther 1990; 16: 17–26.Google ScholarPubMed
57 Department of Health, Welsh Office, Scottish Home and Health Department and Department of Health and Social Security, Northern Ireland. Report on Confidential Enquiries into Maternal Deaths in the United Kingdom 1988–90. London: HMSO, 1994.Google Scholar
58Fishburne, JI, Brenner, WE, Braaksma, JT, Hendricks, CH. Bronchospasm complicating intravenous prostaglandin F2α for therapeutic abortion. Obstet Gynecol 1972; 39: 892–96.Google Scholar
59Hyman, AL, Spannhake, EW, Kadowitz, QJ. Prostaglandins and the lung: state of the art. Am Rev Respir Dis 1978; 117: 111–36.Google Scholar