Science is an intregal part of culture, which moves in the medium of symbols and interpretations. In its epistemic form science also consists of symbolic constructions and interpretations. These make neither themselves nor the world that they describe definite. The driving force behind science and behind scientific culture (which in a deeper understanding are only one) is a research imperative whose efficiency results in the formation of a Leonardo-World, i.e. the modern world as the work of homo faber.