Published online by Cambridge University Press: 16 April 2020
The present study evaluated the association between the WHO (Ten) Well-being index and major depression assessed by the Major Depression Inventory (MDI) and Schedules for Clinical Assessment in Neuropsychiatry (SCAN). The main aim was to examine how well the WHO (Ten) Well-being index worked as a screening instrument for depression in a population-based sample.
A questionnaire including the WHO (Ten) Well-being index and the MDI was sent out to a randomly selected adult Swedish population and 10 441 persons participated. Psychiatrists using SCAN interviewed a selected sample. Sensitivity, specificity, Receiver Operating Characteristics (ROC) and Area Under the Curve (AUC) were calculated.
When a cut-off score ≤ 8 for the Well-being scale was used and depression according to SCAN was the index of validity the sensitivity was 0.81 and the specificity 0.81. When depression according to the algorithm of the MDI was used the sensitivity was 0.89 and the specificity was 0.86 at a cut-off score of ≤ 12. There were no age or gender differences between true positive persons versus false negative persons. The AUC was good (0.86) when using SCAN and when using the DSM-IV algorithm of the MDI excellent (0.93).
The WHO (Ten) Well-being scale can be used as s simple screening instrument for depression in population-based studies. However, the scale needs to be further evaluated in order to examine if the recommended cut-off score in the present study could be replicated in other surveys.
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