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What do we know about the aetiology of late-onset schizophrenia?

Published online by Cambridge University Press:  16 April 2020

DJ Castle  and
R Howard
DJ Castle
Affiliation:
Genetics Institute of Psychiatry, De Crespigny Park, London, SE5 8AF, UK
R Howard
Affiliation:
Old Age Psychiatry Sections, Institute of Psychiatry, De Crespigny Park, London, SE5 8AF, UK
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Summary

Late-onset schizophrenia remains an understudied area. Neuroimaging techniques, which have been widely employed in the study of earlier-onset schizophrenic patients, have only recently been applied to patients with a later onset of illness. This paper reviews current knowledge about brain abnormalities in late-onset schizophrenia, and attempts an integration of the findings with clinical, genetic and epidemiological factors which pertain in such disorders. Suggestions are made for future research regarding this group of patients.

Keywords

late-onset schizophrenianeuroimagingaetiologygenetics
Type
Review
Information
European Psychiatry , Volume 7 , Issue 3 , 1992 , pp. 99 - 108
Copyright
Copyright © Elsevier, Paris 1992

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