Social cognition appears to be an important mediating factor between cognitive and social functioning in schizophrenia which may increase the efficacy of different cognitive-behavioural therapies. In fact, social cognition is becoming a specific target of these interventions, including psychoeducation, cognitive remediation, social skills training and cognitive therapy for positive symptoms. By means of a systematic literature review, main publications about possible efficacy of social cognition in four major languages (English, Spanish, French, and German) are selected. According to this review, main empirical results concerning therapy of social cognition in schizophrenia, both in research and clinical settings, are shown in this presentation. Finally, some practical recommendations about these therapies are provided.