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Therapeutic characteristics of patients followed for bipolar disorder with rapid cycles: Study on a Tunisian population

Published online by Cambridge University Press:  01 September 2022

M. Karoui ,
G. Amri ,
R. Kammoun ,
H. Nefzi  and
F. Ellouz
M. Karoui*
Affiliation:
Razi hospital, Psychiatry G Department, Mannouba, Tunisia
G. Amri
Affiliation:
Razi Hospital, Manouba, tunis, Tunisia
R. Kammoun
Affiliation:
Razi hospital, Psychiatry G, manouba, Tunisia
H. Nefzi
Affiliation:
Razi hospital, Psychiatry G Department, Mannouba, Tunisia
F. Ellouz
Affiliation:
Razi hospital, Psychiatry G, denden, Tunisia
*
*Corresponding author.

Abstract

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Introduction

Bipolar disorder is a frequent and particularly severe psychiatric pathology that causes significant morbidity and mortality. The rapid cycling forms are more severe in terms of their expression, evolutionary course, therapeutic responses and associated comorbidities.

Objectives

The aim of this study is to conduct a descriptive assessment of therapeutic characteristics in patients with rapid cycling bipolar disorder.

Methods

Our work involved a population of 97 patients followed for bipolar disorder diagnosed according to DSM5 criteria, including 37 patients meeting the specification “with rapid cycles”. The patients were divided into two groups: - Group of patients with bipolar disorder with rapid cycles (TBCR) - Group of patients with bipolar disorder without rapid cycling (TBNCR). We compared the therapeutic features among these two groups.

Results

The dominant polarity was depressive in patients with rapid cycles. They required more mood stabilizers. A greater proportion of them had received treatment with serotonin reuptake inhibitor antidepressants. They were more likely to use hypnotics such as antihistamines and zolpidem.

Conclusions

Rapid cycling TB is a relatively common clinical modality that should be investigated and identified.The use of antidepressants is associated with this course of the disease. Their utilization in the treatment of bipolar depression must be thoughtful and well studied

Disclosure

No significant relationships.

Keywords

antidepressantcourserapid cyclingbipolar disorders
Type
Abstract
Information
European Psychiatry , Volume 65 , Special Issue S1: Abstracts of the 30th European Congress of Psychiatry , June 2022 , pp. S415
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of the European Psychiatric Association
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