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The suicidality continuum in a large sample of obsessive–compulsive disorder (OCD) patients

Published online by Cambridge University Press:  23 March 2020

P. Velloso ,
C. Piccinato ,
Y. Ferrão ,
E. Aliende Perin ,
R. Cesar ,
L. Fontenelle ,
A.G. Hounie  and
M.C. do Rosário
P. Velloso*
Affiliation:
Child and Adolescent Psychiatry Unit (UPIA), Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil Obsessive-Compulsive Spectrum Disorder Research Consortium (C-TOC), Brazil
C. Piccinato
Affiliation:
Child and Adolescent Psychiatry Unit (UPIA), Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil Obsessive-Compulsive Spectrum Disorder Research Consortium (C-TOC), Brazil
Y. Ferrão
Affiliation:
Obsessive-Compulsive Spectrum Disorder Research Consortium (C-TOC), Brazil Department of Psychiatry, Health Sciences Federal University of Porto Alegre, Porto Alegre, Brazil
E. Aliende Perin
Affiliation:
Child and Adolescent Psychiatry Unit (UPIA), Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil Obsessive-Compulsive Spectrum Disorder Research Consortium (C-TOC), Brazil
R. Cesar
Affiliation:
Obsessive-Compulsive Spectrum Disorder Research Consortium (C-TOC), Brazil
L. Fontenelle
Affiliation:
Obsessive-Compulsive Spectrum Disorder Research Consortium (C-TOC), Brazil Department of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
A.G. Hounie
Affiliation:
Child and Adolescent Psychiatry Unit (UPIA), Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil Obsessive-Compulsive Spectrum Disorder Research Consortium (C-TOC), Brazil
M.C. do Rosário
Affiliation:
Child and Adolescent Psychiatry Unit (UPIA), Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil Obsessive-Compulsive Spectrum Disorder Research Consortium (C-TOC), Brazil
*
*Corresponding author at: Child and Adolescent Psychiatry Unit (UPIA), Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil. Tel.: +55 11 5576 4990; fax: +55 11 5576 4990. E-mail address:[email protected](P. Velloso).
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Abstract

Background

Obsessive–compulsive disorder (OCD) has a chronic course leading to huge impact in the patient’s functioning. Suicidal thoughts and attempts are much more frequent in OCD subjects than once thought before.

Aim

To empirically investigate whether the suicidal phenomena could be analyzed as a suicidality severity continuum and its association with obsessive–compulsive (OC) symptom dimensions and quality of life (QoL), in a large OCD sample.

Methods

Cross-sectional study with 548 patients diagnosed with OCD according to the DSM-IV criteria, interviewed in the Brazilian OCD Consortium (C-TOC) sites. Patients were evaluated by OCD experts using standardized instruments including: Yale-Brown Obsessive–Compulsive Scale (YBOCS); Dimensional Yale-Brown Obsessive–Compulsive Scale (DYBOCS); Beck Depression and Anxiety Inventories; Structured Clinical Interview for DSM-IV (SCID); and the SF-36 QoL Health Survey.

Results

There were extremely high correlations between all the suicidal phenomena. OCD patients with suicidality had significantly lower QoL, higher severity in the “sexual/religious”, “aggression” and “symmetry/ordering” OC symptom dimensions, higher BDI and BA scores and a higher frequency of suicide attempts in a family member. In the regression analysis, the factors that most impacted suicidality were the sexual dimension severity, the SF-36 QoL Mental Health domain, the severity of depressive symptoms and a relative with an attempted suicide history.

Conclusions

Suicidality could be analyzed as a severity continuum and patients should be carefully monitored since they present with suicidal ideation. Lower QoL scores, higher scores on the sexual dimension and a family history of suicide attempts should be considered as risk factors for suicidality among OCD patients.

Keywords

SuicidalityQuality of lifeOCD
Type
Original article
Information
European Psychiatry , Volume 38 , October 2016 , pp. 1 - 7
Copyright
Copyright © Elsevier Masson SAS 2016

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