Hostname: page-component-78c5997874-s2hrs Total loading time: 0 Render date: 2024-11-05T06:45:40.010Z Has data issue: false hasContentIssue false
  • English
  • Français

Stability of Thought Disorder Index among high-risk and low-risk adoptees in the Finnish adoptive family study of schizophrenia

Published online by Cambridge University Press:  16 April 2020

M. Metsänen ,
K.-E Wahlberg ,
O. Saarento ,
H. Hakko ,
T. Tarvainen ,
P. Koistinen  and
P. Tienari
M. Metsänen*
Affiliation:
Päijät-Häme Central Hospital, Keskussairaalankatu 7, 15850Lahti, Finland
K.-E Wahlberg
Affiliation:
Department of Psychiatry, University of Oulu, Oulu, Finland
O. Saarento
Affiliation:
Clinic of Psychiatry, University Hospital of Oulu, Oulu, Finland
H. Hakko
Affiliation:
Clinic of Psychiatry, University Hospital of Oulu, Oulu, Finland
T. Tarvainen
Affiliation:
Clinic of Psychiatry, University Hospital of Oulu, Oulu, Finland
P. Koistinen
Affiliation:
Clinic of Psychiatry, University Hospital of Oulu, Oulu, Finland
P. Tienari
Affiliation:
Department of Psychiatry, University of Oulu, Oulu, Finland
*
*Corresponding author. E-mail address: [email protected] (M. Metsänen).
Get access

Abstract

The aim of the study was to evaluate whether thought disorders are stable, trait-like features specific to subjects who have a genetic liability to schizophrenia or a psychiatric disorder. The thought disorders of adoptees genetically at high risk (HR) or low risk (LR) for schizophrenia from the Finnish adoptive family study of schizophrenia were evaluated twice at a mean interval of 11 years, using the sum of the Thought Disorder Index (TDI) scores on the Rorschach (TDR). At the initial assessment, the mean TDR scores of women were significantly higher than those of men, while no association between genetic risk and psychiatric status or their interactions with the TDR scores at baseline were found. The main finding was that the initial TDR scores statistically significantly predicted the TDR scores at follow-up, thus indicating the stability of thought disorder over time. However, neither genetic or psychiatric status nor gender or any interaction between these variables associated with TDR at follow-up.

Keywords

Thought disorderSchizophreniaAdoption studyStability of thought disorder
Type
Original article
Information
European Psychiatry , Volume 20 , Issue 1 , January 2005 , pp. 35 - 40
Copyright
Copyright © Elsevier SAS 2005

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Adair, HE, Wagner, EEStability of unusual verbalizations on the Rorschach for outpatients with schizophrenia. J Clin Psychol 1992;48:250–256.3.0.CO;2-P>CrossRefGoogle ScholarPubMed
American Psychiatric Association Diagnostic and statistical manual of mental disorders. 3rd ed. revised. Washington, DC: American Psychiatric Press; 1987.Google Scholar
Asarnow, RF, Maccrimmon, DJAttention/information processing, neuropsychological functioning, and thought disorder during the acute and partial recovery phases of schizophrenia: a longitudinal study. Psychiatry Res 1982;7:309–319.CrossRefGoogle ScholarPubMed
Braff, DL, Glick, ID, Johnson, MH, Zisook, SThe clinical significance of thought disorder across time in psychiatric patients. J Nerv Ment Dis 1988;176:213–220.CrossRefGoogle ScholarPubMed
Caplan, R, Guthrie, D, Tang, B, Nuechterlein, KH, Asarnow, REThought disorder in attention-deficit hyperactivity disorder. J Am Acad Child Adolesc Psychiatr 2001;40:965–972.CrossRefGoogle ScholarPubMed
Dunayevich, E, Keck, PEPrevalence and description of psychotic features in bipolar mania. Curr Psychiatry Rep 2000;2:286–290.CrossRefGoogle ScholarPubMed
Dykens, E, Volkmar, F, Glick, MThought disorder in high-functioning autistic adults. J Autism Dev Disord 1991;21:291–301.CrossRefGoogle ScholarPubMed
Earle-Boyer, EA, Levinson, JC, Grant, R, Harvey, PDThe consistency of thought disorder in mania and schizophrenia. II. An assessment at consecutive admissions. J Nerv Ment Dis 1986;174:443–447.CrossRefGoogle ScholarPubMed
Edell, WSRole of structure in disordered thinking in borderline and schizophrenic disorders. J Pers Assess 1987;51:23–41.CrossRefGoogle ScholarPubMed
Erlenmeyer-Kimling, L, Adamo, UH, Rock, D, Roberts, S, Bassett, A, Squires-Wheeler, Aet al.The New York High-Risk Project. Prevalence and comorbidity of axis I disorders in offspring of schizophrenic parents at 25-year follow-up. Arch Gen Psychiatr 1997;54:1096–1102.CrossRefGoogle ScholarPubMed
Gandolfo, RL, Templer, DI, Cappeletty, GG, Cannon, WGBorderline, depressive and schizophrenic discrimination by MMPI. J Clin Psychol 1991;1:181–186.Google Scholar
Harrow, M, Grossman, LS, Silverstein, ML, Meltzer, HYThought pathology in manic and schizophrenic patients: its occurrence at hospital admission and 7 weeks later. Arch Gen Psychiatr 1982;39:665–671.CrossRefGoogle Scholar
Harvey, PD, Docherty, NM, Serper, MR, Rasmussen, MCognitive deficits and thought disorder: II. An 8-month follow-up study. Schizophr Bull 1990;16:147–156.CrossRefGoogle Scholar
Holzman, PSThought disorder in schizophrenia: editor’s introduction. Schizophr Bull 1986;12:360–372.CrossRefGoogle Scholar
Holzman, PS, Shenton, ME, Solovay, MRQuality of thought disorder in differential diagnosis. Schizophr Bull 1986;12:360–372.CrossRefGoogle ScholarPubMed
Johnston, MH, Holzman, PSAssessing schizophrenic thinkin. San Francisco: Jossey-Bass Publishers; 1979.Google Scholar
Kendler, KS, O’Neill, FA, Burke, J, Murphy, B, Duke, F, Straub, REet al.Irish study of high-density schizophrenia families: field methods and power to detect linkage. Am J Med Genet 1996;67:179–190.3.0.CO;2-N>CrossRefGoogle ScholarPubMed
Marengo, JT, Harrow, MThought disorder in schizophrenia. Tsuang, MT, Simpson, JCHandbook of schizophrenia. Nosology, epidemiology and genetic. Elsevier Science Publishers BV; 1988 85–115.Google Scholar
Marengo, JT, Harrow, MLongitudinal courses of thought disorder in schizophrenia and schizoaffective disorder. Schizophr Bull 1997;23:273–285.CrossRefGoogle ScholarPubMed
Metsänen, M, Wahlberg, K.-E., Saarento, O, Tarvainen, T, Miettunen, J, Koistinen, PEarly presence of thought disorder as a prospective sign of mental disorder. Psychiatry Res 2004;125:193–203.CrossRefGoogle ScholarPubMed
Parnas, J, Cannon, TD, Jacobsen, B, Schulsinger, H, Schulsinger, F, Mednick, SALifetime DSM-III-R diagnostic outcomes in the offspring of schizophrenic mothers. Results from the Copenhagen High-Risk Study. Arch Gen Psychiatr 1993;50:707–714.CrossRefGoogle ScholarPubMed
Ragin, AB, Oltmanns, TFLexical cohesion and formal thought disorder during and after psychotic episodes. J Abnorm Psychol 1986;95:181–183.CrossRefGoogle ScholarPubMed
Rubin, NJ, Arceneaux, JMIntractable depression or psychosis. Acta Psychiatr Scand 2001;104:402–405.CrossRefGoogle ScholarPubMed
Schubert, EW, McNeil, TProspective study of adult mental disturbance in offspring of women with psychosis. Arch Gen Psychiatr 2003;60:473–480.CrossRefGoogle ScholarPubMed
Smith, JE, Hillard, MC, Roll, SRorschach evaluation of adolescent bulimics. Adolescenc 1991;23:687–696.Google Scholar
Solovay, MR, Shenton, ME, Gasperetti, C, Colleman, M, Kestenbaum, E, Carpenter, JTet al.Scoring manual for the thought disorder index. Schizophr Bull 1986;12:483–496.Google ScholarPubMed
Solovay, MR, Shenton, ME, Holzman, PSComparative studies of thought disorder: I. mania and schizophrenia. Arch Gen Psychiatr 1987;44:13–20.CrossRefGoogle Scholar
Strober, M, Freeman, R, Lampter, C, Diamond, J, Kaye, WControlled family study of anorexia nervosa and bulimia nervosa: evidence of shared liability and transmission of partial syndromes. Am J Psychiatr 2000;157:393–401.CrossRefGoogle ScholarPubMed
Tabachnick, BG, Fidell, LSUsing multivariate methods. 2nd e USA: HarperCollins Publisher, Inc; 1989.Google Scholar
Tienari, P, Sorri, A, Lahti, Iet al.Genetic and psychosocial factors in schizophrenia: The Finnish adoptive family study. Schizophr Bull 1987;13:477–484.CrossRefGoogle ScholarPubMed
Tienari, P, Lahti, I, Sorri, A, Naasala, M, Wahlberg, KE, Ronkko, Tet al.The Finnish adoptive family study of schizophrenia: possible joint effects of genetic vulnerability and family interaction. Halweg, K, Goldstein, MJunderstanding major mental disorder: the contribution of family interaction researc New York: Family Process Press; 1987. 33–54.Google Scholar
Tienari, P, Wynne, LC, Moring, J, Läksy, K, Nieminen, P, Sorri, Aet al.Finnish adoptive family study: sample selection and adoptee DSM-III-R diagnoses. Acta Psychiatr Scand 2000;101:433–443.CrossRefGoogle ScholarPubMed
Tienari, P, Wynne, LC, Läksy, KGenetic boundaries of the schizophrenia spectrum: evidence from the Finnish adoptive family study. Am J Psychiatr 2003;160:1–8.CrossRefGoogle ScholarPubMed
Wahlberg, KE, Wynne, LC, Oja, H, Keskitalo, P, Pykäläinen, , Lahti, Iet al.Thought disorder index of Finnish adoptees and communication deviance of their adoptive parents. Psychol Med 2000;30:127–136.CrossRefGoogle ScholarPubMed
Wahlberg, KE, Lyman, CW, Keskitalo, P, Nieminen, P, Moring, J, Läksy, Ket al.Long-term stability of communication deviance. J Abnorm Psycho 2001;110:443–448.CrossRefGoogle ScholarPubMed
Wilcox, JA, Ramirez, AL, Baida-Fragoso, NThe prognostic value of thought disorder in psychotic depression. Ann Clin Psychiatr 2000;12:1–4.CrossRefGoogle ScholarPubMed
Wolff, S‘Schizoid’ personality in childhood and adult life I: the vagaries of diagnostic labelling. Br J Psychiatr 1991;159:615–620.CrossRefGoogle ScholarPubMed
Wolff, S, Townshend, R, Mcguire, RJ, Weeks, DJ‘Schizoid’ personality in childhood and adult life II: adult adjustment and the continuity with schizotypal personality disorder. Br J Psychiatr 1991;159:629–635.CrossRefGoogle ScholarPubMed
Yurgelun-Todd, DA, Killgore, WD, Young, ADSex differences in cerebral tissue volume and cognitive performance during adolescence. Psychol Re 2002;91:743–757.Google ScholarPubMed
Submit a response

Comments

No Comments have been published for this article.