Every human being needs to acquire by interacting with peers, learning and gradually adapted to their socio-cultural environment, attitudes, group, class, gender, provided it fits the circumstances of the environment, personal values to their They come again, a reference system which is considered to be “culture”. You cannot assess psychiatric disorders in isolation, so it is essential to study the socio-cultural context in which it occurs. It is dynamic, its historic time and not everyone integrates alike. Through a case we try to show how culture influences the expression of psychiatric pathology. Specifically, in this patient it is evident that we are beings bio-psycho-social. It is a continuation and must integrate these three areas when assessing a patient. Here we start with a family history unrelated to the Mental Health so that adherence to antipsychotic treatment is guaranteed with monthly administration depot preparation. These socio-cultural factors are the main trigger for the breakdown of the subject that cause the patient psicotización (exacerbations related to stressful situations).