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Sexual Function in Untreated then Treated Schizophrenic Patients: a Prospective Study

Published online by Cambridge University Press:  16 April 2020

Y. El Kissi
Affiliation:
Psychiatry Department, Farhat Hached Hospital, Sousse, Tunisia
J. Mannai
Affiliation:
Psychiatry Department, Farhat Hached Hospital, Sousse, Tunisia
M. Laroussi
Affiliation:
Psychiatry Department, Farhat Hached Hospital, Sousse, Tunisia
S. Gaabout
Affiliation:
Psychiatry Department, Farhat Hached Hospital, Sousse, Tunisia
M. Ayachi
Affiliation:
Psychiatry Department, Farhat Hached Hospital, Sousse, Tunisia
B. Ben Hadj Ali
Affiliation:
Psychiatry Department, Farhat Hached Hospital, Sousse, Tunisia

Abstract

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Introduction

High prevalence of impaired sexual function in patients with schizophrenia has been reported by several studies. Various factors were incriminated including the disease itself, the low level of social competence and treatmentside effects.

Objective

To compare sexual function in drug free schizophrenic patients and six months after initializing antipsychotic treatment.

Methods

A consecutive sample of 109 patients meeting DSM-IV criteria of schizophrenia was constituted in psychiatry department of Farhat Hached hospital (Sousse, Tunisia), during a twenty four months period. They were drug naïve or drug free for at least three months. Assessment was performed at two time points:

T0: During an acute phase of the disease as defined by a BPRS global score ≥ 40 T1: six months after antipsychotic treatment.

Assessment of sexual function used the Arizona Sexual Experience Scale (ASEX).

Results

Sexual function was impaired under antipsychotic treatment. In fact, we noticed lower global score of asex (p = 0.03) and lower subscores of drive (p = 0.015), arousal (p = 0.006), erection or vaginal lubrication (p= 0.010), orgasm (p= 0.001) and satisfaction (p= 0.005).

Conclusion

Sexual function was impaired in patients under antipsychotic drugs, according to global score and to diffrent sexual dimensions subscores. This results seem to, prospectively, confirm the implication of treatment in sexual dysfunction occurence among schizophrenic patients.

Type
P03-209
Copyright
Copyright © European Psychiatric Association 2011
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