Mood disorders can be considered as a pathology of Freedom in human being.

Manic patients feel under-responsible and depressives feel hyper-responsible. Both require from psychotherapist care for risk of suicide and innapropriate behaviour, but also empathy, support, and help from responsible others, relations and doctors. This responsibility is moral, juridic and penal.

We will discuss what Ethic for responsibility can be the right one for clinicians and therapists. We will also discuss which symptom or clinical features are the most hindering for responsibility in depressives. We will conclude that ethical basis is fundamental for right management in therapy.